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STRINGSTRING
RB1CC1 RB1CC1 HPCAL1 HPCAL1 SCLT1 SCLT1 C6orf170 C6orf170 OR2AT4 OR2AT4 SPOCD1 SPOCD1 FAM166A FAM166A OR5K4 OR5K4 OR1K1 OR1K1 OR52W1 OR52W1 BOD1L1 BOD1L1
"C6orf170" - chromosome 6 open reading frame 170 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
C6orf170chromosome 6 open reading frame 170; Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling (By similarity) (1257 aa)    
Predicted Functional Partners:
RB1CC1
RB1-inducible coiled-coil 1; Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double- membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensib [...] (1594 aa)
        score_image       0.710
HPCAL1
hippocalcin-like 1; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (193 aa)
            score_image   0.582
OR5K4
olfactory receptor, family 5, subfamily K, member 4; Odorant receptor (Potential) (321 aa)
            score_image   0.581
OR1K1
olfactory receptor, family 1, subfamily K, member 1; Odorant receptor (Potential) (316 aa)
            score_image   0.580
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4; Odorant receptor (Potential) (320 aa)
            score_image   0.562
FAM166A
family with sequence similarity 166, member A (317 aa)
            score_image   0.561
OR52W1
olfactory receptor, family 52, subfamily W, member 1; Odorant receptor (Potential) (320 aa)
            score_image   0.560
BOD1L1
biorientation of chromosomes in cell division 1-like 1 (3051 aa)
            score_image   0.474
SPOCD1
SPOC domain containing 1 (1216 aa)
            score_image   0.455
SCLT1
sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity) (688 aa)
            score_image   0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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