node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSG00000250021 | GRB14 | ENSP00000381377 | ENSP00000263915 | C15orf38-AP3S2 readthrough | growth factor receptor-bound protein 14; Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal | 0.471 |
ENSG00000250021 | HMG20A | ENSP00000381377 | ENSP00000336856 | C15orf38-AP3S2 readthrough | high mobility group 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4 (By similarity) | 0.501 |
ENSG00000250021 | KIAA1984 | ENSP00000381377 | ENSP00000338013 | C15orf38-AP3S2 readthrough | KIAA1984 | 0.472 |
ENSG00000250021 | LDLRAD1 | ENSP00000381377 | ENSP00000360411 | C15orf38-AP3S2 readthrough | low density lipoprotein receptor class A domain containing 1 | 0.503 |
ENSG00000250021 | MSANTD1 | ENSP00000381377 | ENSP00000411584 | C15orf38-AP3S2 readthrough | Myb/SANT-like DNA-binding domain containing 1 | 0.561 |
ENSG00000250021 | OR10S1 | ENSP00000381377 | ENSP00000431914 | C15orf38-AP3S2 readthrough | olfactory receptor, family 10, subfamily S, member 1; Odorant receptor (Potential) | 0.508 |
ENSG00000250021 | SLCO1B7 | ENSP00000381377 | ENSP00000394168 | C15orf38-AP3S2 readthrough | solute carrier organic anion transporter family, member 1B7 (non-functional) | 0.504 |
ENSG00000250021 | ST6GAL1 | ENSP00000381377 | ENSP00000169298 | C15orf38-AP3S2 readthrough | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; Transfers sialic acid from the donor of substrate CMP- sialic acid to galactose containing acceptor substrates | 0.473 |
ENSG00000250021 | UBC | ENSP00000381377 | ENSP00000344818 | C15orf38-AP3S2 readthrough | ubiquitin C | 0.854 |
ENSG00000250021 | VPS26A | ENSP00000381377 | ENSP00000263559 | C15orf38-AP3S2 readthrough | vacuolar protein sorting 26 homolog A (S. pombe); Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA) | 0.562 |
GRB14 | ENSG00000250021 | ENSP00000263915 | ENSP00000381377 | growth factor receptor-bound protein 14; Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal | C15orf38-AP3S2 readthrough | 0.471 |
HMG20A | ENSG00000250021 | ENSP00000336856 | ENSP00000381377 | high mobility group 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4 (By similarity) | C15orf38-AP3S2 readthrough | 0.501 |
HMG20A | UBC | ENSP00000336856 | ENSP00000344818 | high mobility group 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4 (By similarity) | ubiquitin C | 0.510 |
KIAA1984 | ENSG00000250021 | ENSP00000338013 | ENSP00000381377 | KIAA1984 | C15orf38-AP3S2 readthrough | 0.472 |
LDLRAD1 | ENSG00000250021 | ENSP00000360411 | ENSP00000381377 | low density lipoprotein receptor class A domain containing 1 | C15orf38-AP3S2 readthrough | 0.503 |
LDLRAD1 | MSANTD1 | ENSP00000360411 | ENSP00000411584 | low density lipoprotein receptor class A domain containing 1 | Myb/SANT-like DNA-binding domain containing 1 | 0.700 |
LDLRAD1 | OR10S1 | ENSP00000360411 | ENSP00000431914 | low density lipoprotein receptor class A domain containing 1 | olfactory receptor, family 10, subfamily S, member 1; Odorant receptor (Potential) | 0.643 |
LDLRAD1 | SLCO1B7 | ENSP00000360411 | ENSP00000394168 | low density lipoprotein receptor class A domain containing 1 | solute carrier organic anion transporter family, member 1B7 (non-functional) | 0.633 |
MSANTD1 | ENSG00000250021 | ENSP00000411584 | ENSP00000381377 | Myb/SANT-like DNA-binding domain containing 1 | C15orf38-AP3S2 readthrough | 0.561 |
MSANTD1 | LDLRAD1 | ENSP00000411584 | ENSP00000360411 | Myb/SANT-like DNA-binding domain containing 1 | low density lipoprotein receptor class A domain containing 1 | 0.700 |