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ROBO2 ROBO2 C10orf55 C10orf55 CHCHD1 CHCHD1 ROBO1 ROBO1 CCDC155 CCDC155 ZSWIM8 ZSWIM8 UBC UBC CSNK1E CSNK1E TCEB1 TCEB1 TMEM53 TMEM53 FAM115C FAM115C
"ZSWIM8" - zinc finger, SWIM-type containing 8 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZSWIM8zinc finger, SWIM-type containing 8 (1842 aa)    
Predicted Functional Partners:
CCDC155
coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity) (562 aa)
            score_image   0.647
UBC
ubiquitin C (685 aa)
        score_image       0.633
C10orf55
chromosome 10 open reading frame 55 (151 aa)
            score_image   0.582
CSNK1E
casein kinase 1, epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation (416 aa)
        score_image       0.565
CHCHD1
coiled-coil-helix-coiled-coil-helix domain containing 1 (118 aa)
            score_image   0.539
FAM115C
family with sequence similarity 115, member C (845 aa)
            score_image   0.471
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (112 aa)
        score_image       0.433
TMEM53
transmembrane protein 53 (277 aa)
            score_image   0.416
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila); Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development (1651 aa)
      score_image score_image       0.406
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila); Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (1394 aa)
      score_image score_image       0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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