Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
FAM129C FAM129C ZFP14 ZFP14 C9orf85 C9orf85 UBN2 UBN2 SLC25A45 SLC25A45 SLC25A35 SLC25A35 MUC20 MUC20 PARD3B PARD3B NDUFB10 NDUFB10
"SLC25A45" - solute carrier family 25, member 45 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A45solute carrier family 25, member 45 (288 aa)    
Predicted Functional Partners:
C9orf85
chromosome 9 open reading frame 85 (157 aa)
            score_image   0.720
SLC25A35
solute carrier family 25, member 35 (295 aa)
            score_image   0.640
ZFP14
zinc finger protein 14 homolog (mouse); May be involved in transcriptional regulation (533 aa)
            score_image   0.532
FAM129C
family with sequence similarity 129, member C (697 aa)
            score_image   0.503
UBN2
ubinuclein 2 (1347 aa)
            score_image   0.499
PARD3B
par-3 partitioning defective 3 homolog B (C. elegans); Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions (1143 aa)
            score_image   0.459
MUC20
mucin 20, cell surface associated; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (723 aa)
            score_image   0.457
NDUFB10
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (172 aa)
      score_image     score_image   0.417
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (53%)