SAC3D1 protein (Homo sapiens) - STRING network view

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SAC3D1

SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity) (358 aa)

Predicted Functional Partners:

SHFM1

0.999

STAT5B

0.889

STAT5A

0.887

PCID2

0.843

NUP107

0.823

TPR

0.803

CETN1

0.781

RAE1

0.781

CETN2

0.760

SEC13

0.759

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CETN1	PCID2	ENSP00000319052	ENSP00000337405	centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function	PCI domain containing 2	0.539
CETN1	SAC3D1	ENSP00000319052	ENSP00000381824	centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	0.781
CETN1	TPR	ENSP00000319052	ENSP00000356448	centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function	translocated promoter region, nuclear basket protein; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates t [...]	0.673
CETN2	PCID2	ENSP00000359300	ENSP00000337405	centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110	PCI domain containing 2	0.539
CETN2	SAC3D1	ENSP00000359300	ENSP00000381824	centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	0.760
CETN2	TPR	ENSP00000359300	ENSP00000356448	centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110	translocated promoter region, nuclear basket protein; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates t [...]	0.663
NUP107	RAE1	ENSP00000229179	ENSP00000360286	nucleoporin 107kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	0.968
NUP107	SAC3D1	ENSP00000229179	ENSP00000381824	nucleoporin 107kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	0.823
NUP107	SEC13	ENSP00000229179	ENSP00000312122	nucleoporin 107kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC	SEC13 homolog (S. cerevisiae); Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles	0.999
NUP107	TPR	ENSP00000229179	ENSP00000356448	nucleoporin 107kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC	translocated promoter region, nuclear basket protein; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates t [...]	0.991
PCID2	CETN1	ENSP00000337405	ENSP00000319052	PCI domain containing 2	centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function	0.539
PCID2	CETN2	ENSP00000337405	ENSP00000359300	PCI domain containing 2	centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110	0.539
PCID2	SAC3D1	ENSP00000337405	ENSP00000381824	PCI domain containing 2	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	0.843
PCID2	SHFM1	ENSP00000337405	ENSP00000248566	PCI domain containing 2	split hand/foot malformation (ectrodactyly) type 1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis	0.999
RAE1	NUP107	ENSP00000360286	ENSP00000229179	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	nucleoporin 107kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC	0.968
RAE1	SAC3D1	ENSP00000360286	ENSP00000381824	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	0.781
RAE1	SEC13	ENSP00000360286	ENSP00000312122	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	SEC13 homolog (S. cerevisiae); Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles	0.471
RAE1	TPR	ENSP00000360286	ENSP00000356448	RAE1 RNA export 1 homolog (S. pombe); Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton	translocated promoter region, nuclear basket protein; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates t [...]	0.941
SAC3D1	CETN1	ENSP00000381824	ENSP00000319052	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	centrin, EF-hand protein, 1; Plays a fundamental role in microtubule-organizing center structure and function	0.781
SAC3D1	CETN2	ENSP00000381824	ENSP00000359300	SAC3 domain containing 1; Involved in centrosome duplication and mitotic progression (By similarity)	centrin, EF-hand protein, 2; Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110	0.760

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