node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DLG5 | DTNA | ENSP00000361467 | ENSP00000382064 | discs, large homolog 5 (Drosophila) | dystrobrevin, alpha | 0.858 |
DMD | DTNA | ENSP00000354923 | ENSP00000382064 | dystrophin | dystrobrevin, alpha | 0.978 |
DMD | SNTA1 | ENSP00000354923 | ENSP00000217381 | dystrophin | syntrophin, alpha 1; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5- bisphosphate (By similarity) | 0.999 |
DMD | SNTB1 | ENSP00000354923 | ENSP00000378965 | dystrophin | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1); Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex | 0.982 |
DMD | SNTB2 | ENSP00000354923 | ENSP00000338191 | dystrophin | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN | 0.918 |
DMD | SYNC | ENSP00000354923 | ENSP00000386439 | dystrophin | syncoilin, intermediate filament protein | 0.601 |
DMD | UTRN | ENSP00000354923 | ENSP00000356515 | dystrophin | utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) | 0.962 |
DTNA | DLG5 | ENSP00000382064 | ENSP00000361467 | dystrobrevin, alpha | discs, large homolog 5 (Drosophila) | 0.858 |
DTNA | DMD | ENSP00000382064 | ENSP00000354923 | dystrobrevin, alpha | dystrophin | 0.978 |
DTNA | NDUFB10 | ENSP00000382064 | ENSP00000268668 | dystrobrevin, alpha | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | 0.858 |
DTNA | P4HB | ENSP00000382064 | ENSP00000327801 | dystrobrevin, alpha | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | 0.796 |
DTNA | SEC24C | ENSP00000382064 | ENSP00000321845 | dystrobrevin, alpha | SEC24 family, member C (S. cerevisiae); Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex | 0.899 |
DTNA | SNTA1 | ENSP00000382064 | ENSP00000217381 | dystrobrevin, alpha | syntrophin, alpha 1; Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5- bisphosphate (By similarity) | 0.964 |
DTNA | SNTB1 | ENSP00000382064 | ENSP00000378965 | dystrobrevin, alpha | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1); Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex | 0.919 |
DTNA | SNTB2 | ENSP00000382064 | ENSP00000338191 | dystrobrevin, alpha | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN | 0.885 |
DTNA | SYNC | ENSP00000382064 | ENSP00000386439 | dystrobrevin, alpha | syncoilin, intermediate filament protein | 0.891 |
DTNA | UTRN | ENSP00000382064 | ENSP00000356515 | dystrobrevin, alpha | utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) | 0.946 |
NDUFB10 | DTNA | ENSP00000268668 | ENSP00000382064 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | dystrobrevin, alpha | 0.858 |
P4HB | DTNA | ENSP00000327801 | ENSP00000382064 | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | dystrobrevin, alpha | 0.796 |
SEC24C | DTNA | ENSP00000321845 | ENSP00000382064 | SEC24 family, member C (S. cerevisiae); Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex | dystrobrevin, alpha | 0.899 |