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SDR39U1 SDR39U1 CISD1 CISD1 SPAG9 SPAG9 CISD2 CISD2 AIFM3 AIFM3 DMGDH DMGDH TOP2A TOP2A ACLY ACLY UROD UROD L2HGDH L2HGDH DPYD DPYD
"AIFM3" - apoptosis-inducing factor, mitochondrion-associated, 3 in Homo sapiens
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Known Interactions
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Predicted Interactions
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AIFM3apoptosis-inducing factor, mitochondrion-associated, 3; Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential (605 aa)    
Predicted Functional Partners:
CISD1
CDGSH iron sulfur domain 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions (108 aa)
      score_image score_image       0.686
CISD2
CDGSH iron sulfur domain 2; Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy (135 aa)
      score_image score_image       0.686
L2HGDH
L-2-hydroxyglutarate dehydrogenase (463 aa)
score_image     score_image     score_image   0.676
DMGDH
dimethylglycine dehydrogenase (866 aa)
score_image     score_image score_image   score_image   0.625
ACLY
ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine (1101 aa)
      score_image     score_image   0.608
UROD
uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (367 aa)
      score_image     score_image   0.598
DPYD
dihydropyrimidine dehydrogenase (1025 aa)
score_image           score_image   0.597
SPAG9
sperm associated antigen 9 (1321 aa)
            score_image   0.593
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1; Putative NADP-dependent oxidoreductase (293 aa)
      score_image         0.585
TOP2A
topoisomerase (DNA) II alpha 170kDa (1531 aa)
            score_image   0.575
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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