node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EBNA1BP2 | FTSJ3 | ENSP00000407323 | ENSP00000396673 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.999 |
EBNA1BP2 | GNL3 | ENSP00000407323 | ENSP00000395772 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) | 0.998 |
EBNA1BP2 | MKI67IP | ENSP00000407323 | ENSP00000285814 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.993 |
EBNA1BP2 | NOC2L | ENSP00000407323 | ENSP00000317992 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter | 0.984 |
EBNA1BP2 | NOP2 | ENSP00000407323 | ENSP00000382392 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.999 |
EBNA1BP2 | NOP56 | ENSP00000407323 | ENSP00000370589 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.991 |
EBNA1BP2 | NOP58 | ENSP00000407323 | ENSP00000264279 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity) | 0.988 |
EBNA1BP2 | RBM28 | ENSP00000407323 | ENSP00000223073 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes | 0.946 |
EBNA1BP2 | RPF2 | ENSP00000407323 | ENSP00000402338 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | ribosome production factor 2 homolog (S. cerevisiae) | 0.999 |
EBNA1BP2 | RRS1 | ENSP00000407323 | ENSP00000322396 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) | 0.999 |
FTSJ3 | EBNA1BP2 | ENSP00000396673 | ENSP00000407323 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | 0.999 |
FTSJ3 | GNL3 | ENSP00000396673 | ENSP00000395772 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) | 0.998 |
FTSJ3 | MKI67IP | ENSP00000396673 | ENSP00000285814 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.999 |
FTSJ3 | NOC2L | ENSP00000396673 | ENSP00000317992 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter | 0.940 |
FTSJ3 | NOP2 | ENSP00000396673 | ENSP00000382392 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.999 |
FTSJ3 | NOP56 | ENSP00000396673 | ENSP00000370589 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.998 |
FTSJ3 | NOP58 | ENSP00000396673 | ENSP00000264279 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity) | 0.998 |
FTSJ3 | RBM28 | ENSP00000396673 | ENSP00000223073 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes | 0.988 |
FTSJ3 | RPF2 | ENSP00000396673 | ENSP00000402338 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | ribosome production factor 2 homolog (S. cerevisiae) | 0.980 |
FTSJ3 | RRS1 | ENSP00000396673 | ENSP00000322396 | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) | 0.994 |