HEATR7B2 protein (Homo sapiens) - STRING network view

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HEATR7B2

HEAT repeat family member 7B2 (1585 aa)

Predicted Functional Partners:

UGP2

0.644

CHAC1

0.587

C10orf118

0.587

KIF27

0.530

ZC3H14

0.522

SMYD2

0.513

SAA1

0.491

CSN3

0.485

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf118	HEATR7B2	ENSP00000358293	ENSP00000382476	chromosome 10 open reading frame 118	HEAT repeat family member 7B2	0.587
CHAC1	HEATR7B2	ENSP00000398105	ENSP00000382476	ChaC, cation transport regulator homolog 1 (E. coli); Negative regulator of Notch signaling pathway involved in embryonic neurogenesis- acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade	HEAT repeat family member 7B2	0.587
CSN3	HEATR7B2	ENSP00000304822	ENSP00000382476	casein kappa; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk	HEAT repeat family member 7B2	0.485
HEATR7B2	C10orf118	ENSP00000382476	ENSP00000358293	HEAT repeat family member 7B2	chromosome 10 open reading frame 118	0.587
HEATR7B2	CHAC1	ENSP00000382476	ENSP00000398105	HEAT repeat family member 7B2	ChaC, cation transport regulator homolog 1 (E. coli); Negative regulator of Notch signaling pathway involved in embryonic neurogenesis- acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade	0.587
HEATR7B2	CSN3	ENSP00000382476	ENSP00000304822	HEAT repeat family member 7B2	casein kappa; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk	0.485
HEATR7B2	KIF27	ENSP00000382476	ENSP00000297814	HEAT repeat family member 7B2	kinesin family member 27; Plays an essential role in motile ciliogenesis (By similarity)	0.530
HEATR7B2	SAA1	ENSP00000382476	ENSP00000348918	HEAT repeat family member 7B2	serum amyloid A1; Major acute phase reactant. Apolipoprotein of the HDL complex (By similarity)	0.491
HEATR7B2	SMYD2	ENSP00000382476	ENSP00000355924	HEAT repeat family member 7B2	SET and MYND domain containing 2; Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 ’Lys-4’ (H3K4me) and dimethylates histone H3 ’Lys-36’ (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates ’Lys-370’ of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates ’Lys-860’ of RB1/RB	0.513
HEATR7B2	UGP2	ENSP00000382476	ENSP00000338703	HEAT repeat family member 7B2	UDP-glucose pyrophosphorylase 2; Plays a central role as a glucosyl donor in cellular metabolic pathways	0.644
HEATR7B2	ZC3H14	ENSP00000382476	ENSP00000251038	HEAT repeat family member 7B2	zinc finger CCCH-type containing 14	0.522
KIF27	HEATR7B2	ENSP00000297814	ENSP00000382476	kinesin family member 27; Plays an essential role in motile ciliogenesis (By similarity)	HEAT repeat family member 7B2	0.530
SAA1	HEATR7B2	ENSP00000348918	ENSP00000382476	serum amyloid A1; Major acute phase reactant. Apolipoprotein of the HDL complex (By similarity)	HEAT repeat family member 7B2	0.491
SMYD2	HEATR7B2	ENSP00000355924	ENSP00000382476	SET and MYND domain containing 2; Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 ’Lys-4’ (H3K4me) and dimethylates histone H3 ’Lys-36’ (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates ’Lys-370’ of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates ’Lys-860’ of RB1/RB	HEAT repeat family member 7B2	0.513
UGP2	HEATR7B2	ENSP00000338703	ENSP00000382476	UDP-glucose pyrophosphorylase 2; Plays a central role as a glucosyl donor in cellular metabolic pathways	HEAT repeat family member 7B2	0.644
ZC3H14	HEATR7B2	ENSP00000251038	ENSP00000382476	zinc finger CCCH-type containing 14	HEAT repeat family member 7B2	0.522

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