Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | C14orf164 | chromosome 14 open reading frame 164 (300 aa) | ||||||||||||
Predicted Functional Partners:
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 | C14orf64 | chromosome 14 open reading frame 64 (137 aa) |
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0.811 | ||||||||||
 | CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis (277 aa) |
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0.569 | ||||||||||
 | MSH4 | mutS homolog 4 (E. coli); Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis (936 aa) |
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0.564 | ||||||||
 | MSH5 | mutS homolog 5 (E. coli) (835 aa) |
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0.545 | |||||||||
 | CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5; Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins (702 aa) |
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0.470 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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