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STRINGSTRING
PPP1R12B PPP1R12B MYH3 MYH3 MYH8 MYH8 MYH10 MYH10 MYH11 MYH11 MYL5 MYL5 MYH1 MYH1 MYH9 MYH9 MYH14 MYH14 PPP1R12C PPP1R12C PPP1R12A PPP1R12A
"MYL5" - myosin, light chain 5, regulatory in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYL5myosin, light chain 5, regulatory (173 aa)    
Predicted Functional Partners:
MYH14
myosin, heavy chain 14, non-muscle (2036 aa)
      score_image score_image score_image score_image   0.927
PPP1R12A
protein phosphatase 1, regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity (1030 aa)
        score_image score_image score_image   0.922
MYH10
myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (1976 aa)
      score_image score_image score_image score_image   0.922
PPP1R12B
protein phosphatase 1, regulatory subunit 12B (982 aa)
        score_image score_image score_image   0.919
PPP1R12C
protein phosphatase 1, regulatory subunit 12C; Regulates myosin phosphatase activity (782 aa)
        score_image score_image score_image   0.919
MYH9
myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping (1960 aa)
      score_image score_image score_image score_image   0.916
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic; Muscle contraction (1940 aa)
      score_image score_image score_image score_image   0.915
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal; Muscle contraction (1937 aa)
      score_image score_image score_image score_image   0.914
MYH1
myosin, heavy chain 1, skeletal muscle, adult; Muscle contraction (1939 aa)
      score_image score_image score_image score_image   0.883
MYH11
myosin, heavy chain 11, smooth muscle; Muscle contraction (1979 aa)
      score_image score_image score_image score_image   0.875
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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