SELM protein (Homo sapiens) - STRING network view

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Score

SELM

selenoprotein M precursor ; May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation (By similarity) (145 aa)

Predicted Functional Partners:

SELO

0.908

SELK

0.841

SEPN1

0.815

VIMP

0.812

SEPW1

0.804

SEP15

0.754

GPX1

0.656

C11orf31

0.650

SELT

0.615

GPX6

0.593

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf31	GPX1	ENSP00000373509	ENSP00000407375	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	0.630
C11orf31	GPX6	ENSP00000373509	ENSP00000354581	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	glutathione peroxidase 6 (olfactory)	0.475
C11orf31	SELK	ENSP00000373509	ENSP00000418813	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	selenoprotein K	0.720
C11orf31	SELM	ENSP00000373509	ENSP00000383155	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	selenoprotein M precursor ; May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation (By similarity)	0.650
C11orf31	SELO	ENSP00000373509	ENSP00000370288	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	selenoprotein O	0.666
C11orf31	SELT	ENSP00000373509	ENSP00000418910	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	selenoprotein T precursor	0.753
C11orf31	SEP15	ENSP00000373509	ENSP00000328729	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	15 kDa selenoprotein isoform 1 precursor ; May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity)	0.634
C11orf31	SEPN1	ENSP00000373509	ENSP00000355141	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	selenoprotein N, 1	0.583
C11orf31	SEPW1	ENSP00000373509	ENSP00000422644	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	selenoprotein W, 1; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity)	0.772
C11orf31	VIMP	ENSP00000373509	ENSP00000381282	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	VCP-interacting membrane protein; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination	0.812
GPX1	C11orf31	ENSP00000407375	ENSP00000373509	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	0.630
GPX1	SELK	ENSP00000407375	ENSP00000418813	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	selenoprotein K	0.596
GPX1	SELM	ENSP00000407375	ENSP00000383155	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	selenoprotein M precursor ; May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation (By similarity)	0.656
GPX1	SELO	ENSP00000407375	ENSP00000370288	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	selenoprotein O	0.500
GPX1	SELT	ENSP00000407375	ENSP00000418910	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	selenoprotein T precursor	0.587
GPX1	SEP15	ENSP00000407375	ENSP00000328729	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	15 kDa selenoprotein isoform 1 precursor ; May be involved in redox reactions associated with the formation of disulfide bonds. May contribute to the quality control of protein folding in the endoplasmic reticulum (By similarity)	0.673
GPX1	SEPN1	ENSP00000407375	ENSP00000355141	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	selenoprotein N, 1	0.472
GPX1	SEPW1	ENSP00000407375	ENSP00000422644	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	selenoprotein W, 1; Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency (By similarity)	0.647
GPX1	VIMP	ENSP00000407375	ENSP00000381282	glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown	VCP-interacting membrane protein; Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination	0.818
GPX6	C11orf31	ENSP00000354581	ENSP00000373509	glutathione peroxidase 6 (olfactory)	chromosome 11 open reading frame 31; May be involved in a redox-related process (Potential)	0.475

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