TMEM242 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMEM242

transmembrane protein 242 (141 aa)

Predicted Functional Partners:

ZDHHC14

0.700

VPS53

0.643

GGT7

0.571

ARID1B

0.501

ARHGAP15

0.472

KIAA0240

0.444

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP15	TMEM242	ENSP00000295095	ENSP00000383594	Rho GTPase activating protein 15	transmembrane protein 242	0.472
ARID1B	TMEM242	ENSP00000344546	ENSP00000383594	AT rich interactive domain 1B (SWI1-like); Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to pos [...]	transmembrane protein 242	0.501
GGT7	TMEM242	ENSP00000338964	ENSP00000383594	gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity)	transmembrane protein 242	0.571
KIAA0240	TMEM242	ENSP00000313933	ENSP00000383594	KIAA0240	transmembrane protein 242	0.444
KIAA0240	VPS53	ENSP00000313933	ENSP00000401435	KIAA0240	vacuolar protein sorting 53 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.586
TMEM242	ARHGAP15	ENSP00000383594	ENSP00000295095	transmembrane protein 242	Rho GTPase activating protein 15	0.472
TMEM242	ARID1B	ENSP00000383594	ENSP00000344546	transmembrane protein 242	AT rich interactive domain 1B (SWI1-like); Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to pos [...]	0.501
TMEM242	GGT7	ENSP00000383594	ENSP00000338964	transmembrane protein 242	gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity)	0.571
TMEM242	KIAA0240	ENSP00000383594	ENSP00000313933	transmembrane protein 242	KIAA0240	0.444
TMEM242	VPS53	ENSP00000383594	ENSP00000401435	transmembrane protein 242	vacuolar protein sorting 53 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.643
TMEM242	ZDHHC14	ENSP00000383594	ENSP00000352821	transmembrane protein 242	zinc finger, DHHC-type containing 14	0.700
VPS53	KIAA0240	ENSP00000401435	ENSP00000313933	vacuolar protein sorting 53 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	KIAA0240	0.586
VPS53	TMEM242	ENSP00000401435	ENSP00000383594	vacuolar protein sorting 53 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	transmembrane protein 242	0.643
ZDHHC14	TMEM242	ENSP00000352821	ENSP00000383594	zinc finger, DHHC-type containing 14	transmembrane protein 242	0.700

Experiments

Cooccurrence

Textmining

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About