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POC5 POC5 CARK CARK SEC16B SEC16B TMEM160 TMEM160 TMEM18 TMEM18 CADM2 CADM2 OR8D4 OR8D4 SIRPB1 SIRPB1 EPB41 EPB41 HMCN1 HMCN1
"CADM2" - cell adhesion molecule 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CADM2cell adhesion molecule 2; Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes (437 aa)    
Predicted Functional Partners:
HMCN1
hemicentin 1 (5635 aa)
        score_image   score_image score_image 0.816
SIRPB1
signal-regulatory protein beta 1; Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK (398 aa)
        score_image     score_image 0.812
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (864 aa)
            score_image   0.749
TMEM18
transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) (140 aa)
            score_image   0.504
POC5
POC5 centriolar protein homolog (Chlamydomonas); Essential for the assembly of the distal half of centrioles, required for centriole elongation (575 aa)
            score_image   0.499
OR8D4
olfactory receptor, family 8, subfamily D, member 4; Odorant receptor (Potential) (314 aa)
            score_image   0.463
TMEM160
transmembrane protein 160 (188 aa)
            score_image   0.453
SEC16B
SEC16 homolog B (S. cerevisiae); Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization (1060 aa)
            score_image   0.416
CARK
FPGT-TNNI3K readthrough; May play a role in cardiac physiology (936 aa)
            score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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