Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | LRP5L | low density lipoprotein receptor-related protein 5-like (252 aa) | ||||||||||||
Predicted Functional Partners:
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 | OR4K2 | olfactory receptor, family 4, subfamily K, member 2; Odorant receptor (Potential) (314 aa) |
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0.702 | ||||||||||
 | OR4N2 | olfactory receptor, family 4, subfamily N, member 2; Odorant receptor (Potential) (307 aa) |
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0.643 | ||||||||||
 | OR4K1 | olfactory receptor, family 4, subfamily K, member 1; Odorant receptor (Potential) (311 aa) |
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0.632 | ||||||||||
 | POTEB | POTE ankyrin domain family, member B (544 aa) |
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0.582 | ||||||||||
 | OR4K5 | olfactory receptor, family 4, subfamily K, member 5; Odorant receptor (Potential) (323 aa) |
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0.566 | ||||||||||
 | OR52E4 | olfactory receptor, family 52, subfamily E, member 4; Odorant receptor (Potential) (312 aa) |
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0.518 | ||||||||||
 | LRP12 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (859 aa) |
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0.478 | ||||||||||
 | FAM5C | family with sequence similarity 5, member C (766 aa) |
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0.473 | ||||||||||
 | ZNF33B | zinc finger protein 33B; May be involved in transcriptional regulation (778 aa) |
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0.472 | ||||||||||
 | TM4SF19 | transmembrane 4 L six family member 19 (209 aa) |
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0.472 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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