GDPD3 protein (Homo sapiens) - STRING network view

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GDPD3

glycerophosphodiester phosphodiesterase domain containing 3 (318 aa)

Predicted Functional Partners:

KCTD13

0.531

TSPO2

0.530

TSPO

0.530

H2AFY

0.518

H2AFY2

0.518

GPD2

0.516

GK5

0.505

GK

0.505

GK2

0.505

SHPK

0.505

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GDPD3	GK	ENSP00000384363	ENSP00000368226	glycerophosphodiester phosphodiesterase domain containing 3	glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism	0.505
GDPD3	GK2	ENSP00000384363	ENSP00000351706	glycerophosphodiester phosphodiesterase domain containing 3	glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)	0.505
GDPD3	GK5	ENSP00000384363	ENSP00000418001	glycerophosphodiester phosphodiesterase domain containing 3	glycerol kinase 5 (putative)	0.505
GDPD3	GPD2	ENSP00000384363	ENSP00000308610	glycerophosphodiester phosphodiesterase domain containing 3	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.516
GDPD3	H2AFY	ENSP00000384363	ENSP00000423563	glycerophosphodiester phosphodiesterase domain containing 3	H2A histone family, member Y; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Involved in stable X chromosome inactiv [...]	0.518
GDPD3	H2AFY2	ENSP00000384363	ENSP00000362352	glycerophosphodiester phosphodiesterase domain containing 3	H2A histone family, member Y2; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome [...]	0.518
GDPD3	KCTD13	ENSP00000384363	ENSP00000311202	glycerophosphodiester phosphodiesterase domain containing 3	potassium channel tetramerisation domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration	0.531
GDPD3	SHPK	ENSP00000384363	ENSP00000225519	glycerophosphodiester phosphodiesterase domain containing 3	sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism (By similarity)	0.505
GDPD3	TSPO	ENSP00000384363	ENSP00000328973	glycerophosphodiester phosphodiesterase domain containing 3	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.530
GDPD3	TSPO2	ENSP00000384363	ENSP00000362255	glycerophosphodiester phosphodiesterase domain containing 3	translocator protein 2; Binds cholesterol and mediates its redistribution during erythropoiesis which may play a role in erythrocyte maturation	0.530
GK	GDPD3	ENSP00000368226	ENSP00000384363	glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism	glycerophosphodiester phosphodiesterase domain containing 3	0.505
GK	GPD2	ENSP00000368226	ENSP00000308610	glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.950
GK2	GDPD3	ENSP00000351706	ENSP00000384363	glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)	glycerophosphodiester phosphodiesterase domain containing 3	0.505
GK2	GPD2	ENSP00000351706	ENSP00000308610	glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.906
GK5	GDPD3	ENSP00000418001	ENSP00000384363	glycerol kinase 5 (putative)	glycerophosphodiester phosphodiesterase domain containing 3	0.505
GK5	GPD2	ENSP00000418001	ENSP00000308610	glycerol kinase 5 (putative)	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.884
GPD2	GDPD3	ENSP00000308610	ENSP00000384363	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	glycerophosphodiester phosphodiesterase domain containing 3	0.516
GPD2	GK	ENSP00000308610	ENSP00000368226	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism	0.950
GPD2	GK2	ENSP00000308610	ENSP00000351706	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)	0.906
GPD2	GK5	ENSP00000308610	ENSP00000418001	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	glycerol kinase 5 (putative)	0.884

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