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STRINGSTRING
ADNP2 ADNP2 WDR72 WDR72 ZNF454 ZNF454 CCDC70 CCDC70 CCDC129 CCDC129 TKTL2 TKTL2 ZNF16 ZNF16
"CCDC129" - coiled-coil domain containing 129 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC129coiled-coil domain containing 129 (1044 aa)    
Predicted Functional Partners:
ZNF454
zinc finger protein 454; May be involved in transcriptional regulation (522 aa)
             score_image   0.567
ZNF16
zinc finger protein 16; May be involved in transcriptional regulation (682 aa)
             score_image   0.472
WDR72
WD repeat domain 72 (1102 aa)
             score_image   0.459
TKTL2
transketolase-like 2; Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (626 aa)
             score_image   0.418
ADNP2
ADNP homeobox 2; May be involved in transcriptional regulation (1131 aa)
             score_image   0.416
CCDC70
coiled-coil domain containing 70 (233 aa)
             score_image   0.412
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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