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STRINGSTRING
LRRC28 LRRC28 MNX1 MNX1 NRXN1 NRXN1 NXPH1 NXPH1 ICA1 ICA1 OR13D1 OR13D1 NPS NPS
"NXPH1" - neurexophilin 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NXPH1neurexophilin 1; May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors (Potential) (271 aa)    
Predicted Functional Partners:
NPS
neuropeptide S; Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity) (89 aa)
            score_image   0.749
NRXN1
neurexin 1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity) (1547 aa)
        score_image   score_image   0.714
MNX1
motor neuron and pancreas homeobox 1; Putative transcription factor involved in pancreas development and function (401 aa)
            score_image   0.567
OR13D1
olfactory receptor, family 13, subfamily D, member 1; Odorant receptor (Potential) (346 aa)
            score_image   0.418
ICA1
islet cell autoantigen 1, 69kDa; May play a role in neurotransmitter secretion (By similarity) (483 aa)
            score_image   0.407
LRRC28
leucine rich repeat containing 28 (367 aa)
            score_image   0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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