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GDF9 GDF9 YWHAQ YWHAQ MC2R MC2R FSHR FSHR FOXO1 FOXO1 ADRB2 ADRB2 POMC POMC VIP VIP GNAS GNAS CGA CGA FSHB FSHB
"FSHR" - follicle stimulating hormone receptor in Homo sapiens
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Predicted Interactions
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FSHRfollicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (695 aa)    
Predicted Functional Partners:
FSHB
follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs (129 aa)
        score_image score_image score_image   0.999
CGA
glycoprotein hormones, alpha polypeptide (116 aa)
        score_image score_image score_image   0.994
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (245 aa)
        score_image   score_image   0.956
GDF9
growth differentiation factor 9; Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells (454 aa)
            score_image   0.942
FOXO1
forkhead box O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5’-TT[G/A]TTTTG-3’ and the related Daf-16 family binding element (DBE) with consensus sequence 5’- TT[G/A]TTTAC-3’. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts syngernistically with ATF4 to suppress osteocalcin/BGL [...] (655 aa)
        score_image   score_image   0.937
VIP
vasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder (170 aa)
          score_image score_image   0.927
ADRB2
adrenoceptor beta 2, surface (413 aa)
          score_image score_image   0.925
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone); Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (297 aa)
          score_image score_image   0.922
GNAS
GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase- it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity) (1037 aa)
          score_image score_image   0.922
POMC
proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)
          score_image score_image   0.921
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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