node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ10B | SMCR8 | ENSP00000263960 | ENSP00000385025 | coenzyme Q10 homolog B (S. cerevisiae); Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity) | Smith-Magenis syndrome chromosome region, candidate 8 | 0.587 |
DHRS7B | DRG2 | ENSP00000378887 | ENSP00000225729 | dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | 0.417 |
DHRS7B | LRRC48 | ENSP00000378887 | ENSP00000326870 | dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) | leucine rich repeat containing 48 | 0.575 |
DHRS7B | SMCR8 | ENSP00000378887 | ENSP00000385025 | dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) | Smith-Magenis syndrome chromosome region, candidate 8 | 0.514 |
DHRS7B | UBC | ENSP00000378887 | ENSP00000344818 | dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) | ubiquitin C | 0.644 |
DRG2 | DHRS7B | ENSP00000225729 | ENSP00000378887 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) | 0.417 |
DRG2 | LRRC48 | ENSP00000225729 | ENSP00000326870 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | leucine rich repeat containing 48 | 0.508 |
DRG2 | NT5M | ENSP00000225729 | ENSP00000373674 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | 5’,3’-nucleotidase, mitochondrial; Dephosphorylates specifically the 5’ and 2’(3’)- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP | 0.547 |
DRG2 | SHMT1 | ENSP00000225729 | ENSP00000318868 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | 0.628 |
DRG2 | SMCR8 | ENSP00000225729 | ENSP00000385025 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | Smith-Magenis syndrome chromosome region, candidate 8 | 0.509 |
DRG2 | UBC | ENSP00000225729 | ENSP00000344818 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | ubiquitin C | 0.957 |
LRRC48 | DHRS7B | ENSP00000326870 | ENSP00000378887 | leucine rich repeat containing 48 | dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) | 0.575 |
LRRC48 | DRG2 | ENSP00000326870 | ENSP00000225729 | leucine rich repeat containing 48 | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | 0.508 |
LRRC48 | NT5M | ENSP00000326870 | ENSP00000373674 | leucine rich repeat containing 48 | 5’,3’-nucleotidase, mitochondrial; Dephosphorylates specifically the 5’ and 2’(3’)- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP | 0.474 |
LRRC48 | SMCR8 | ENSP00000326870 | ENSP00000385025 | leucine rich repeat containing 48 | Smith-Magenis syndrome chromosome region, candidate 8 | 0.612 |
LRRC48 | TOM1L2 | ENSP00000326870 | ENSP00000368818 | leucine rich repeat containing 48 | target of myb1-like 2 (chicken); Probable role in protein transport. May regulate growth factor-induced mitogenic signaling | 0.485 |
NT5M | DRG2 | ENSP00000373674 | ENSP00000225729 | 5’,3’-nucleotidase, mitochondrial; Dephosphorylates specifically the 5’ and 2’(3’)- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP | developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death | 0.547 |
NT5M | LRRC48 | ENSP00000373674 | ENSP00000326870 | 5’,3’-nucleotidase, mitochondrial; Dephosphorylates specifically the 5’ and 2’(3’)- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP | leucine rich repeat containing 48 | 0.474 |
NT5M | SHMT1 | ENSP00000373674 | ENSP00000318868 | 5’,3’-nucleotidase, mitochondrial; Dephosphorylates specifically the 5’ and 2’(3’)- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | 0.578 |
NT5M | SMCR8 | ENSP00000373674 | ENSP00000385025 | 5’,3’-nucleotidase, mitochondrial; Dephosphorylates specifically the 5’ and 2’(3’)- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP | Smith-Magenis syndrome chromosome region, candidate 8 | 0.622 |