| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCY1 | ADCY10 | ENSP00000297323 | ENSP00000356825 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | 0.591 |
| ADCY1 | ADCY2 | ENSP00000297323 | ENSP00000342952 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase | 0.962 |
| ADCY1 | ADCY3 | ENSP00000297323 | ENSP00000260600 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | 0.911 |
| ADCY1 | ADCY4 | ENSP00000297323 | ENSP00000312126 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | 0.915 |
| ADCY1 | ADCY5 | ENSP00000297323 | ENSP00000419361 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.908 |
| ADCY1 | ADCY6 | ENSP00000297323 | ENSP00000311405 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | 0.907 |
| ADCY1 | ADCY7 | ENSP00000297323 | ENSP00000254235 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.924 |
| ADCY1 | ADCY8 | ENSP00000297323 | ENSP00000286355 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.910 |
| ADCY1 | ADCY9 | ENSP00000297323 | ENSP00000294016 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 9; May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity) | 0.928 |
| ADCY1 | PDE7A | ENSP00000297323 | ENSP00000385632 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | phosphodiesterase 7A; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction | 0.964 |
| ADCY10 | ADCY1 | ENSP00000356825 | ENSP00000297323 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | 0.591 |
| ADCY10 | ADCY2 | ENSP00000356825 | ENSP00000342952 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase | 0.573 |
| ADCY10 | ADCY3 | ENSP00000356825 | ENSP00000260600 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration | 0.657 |
| ADCY10 | ADCY4 | ENSP00000356825 | ENSP00000312126 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | 0.572 |
| ADCY10 | ADCY5 | ENSP00000356825 | ENSP00000419361 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.565 |
| ADCY10 | ADCY6 | ENSP00000356825 | ENSP00000311405 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) | 0.574 |
| ADCY10 | ADCY7 | ENSP00000356825 | ENSP00000254235 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.619 |
| ADCY10 | ADCY8 | ENSP00000356825 | ENSP00000286355 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.578 |
| ADCY10 | ADCY9 | ENSP00000356825 | ENSP00000294016 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | adenylate cyclase 9; May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity) | 0.453 |
| ADCY10 | PDE7A | ENSP00000356825 | ENSP00000385632 | adenylate cyclase 10 (soluble); Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation | phosphodiesterase 7A; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction | 0.950 |
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