SEC14L6 protein (Homo sapiens) - STRING network view

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SEC14L6

SEC14-like 6 (S. cerevisiae) (397 aa)

Predicted Functional Partners:

SACM1L

0.575

PLD1

0.547

PLD2

0.547

PCSK2

0.498

KIF22

0.479

PCSK5

0.467

PCSK7

0.467

PCSK1

0.467

PCSK6

0.467

PCSK4

0.467

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIF22	SEC14L6	ENSP00000160827	ENSP00000385695	kinesin family member 22; Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA	SEC14-like 6 (S. cerevisiae)	0.479
PCSK1	PCSK7	ENSP00000308024	ENSP00000325917	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	0.429
PCSK1	SEC14L6	ENSP00000308024	ENSP00000385695	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	SEC14-like 6 (S. cerevisiae)	0.467
PCSK2	PCSK7	ENSP00000262545	ENSP00000325917	proprotein convertase subtilisin/kexin type 2	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	0.430
PCSK2	SEC14L6	ENSP00000262545	ENSP00000385695	proprotein convertase subtilisin/kexin type 2	SEC14-like 6 (S. cerevisiae)	0.498
PCSK4	PCSK7	ENSP00000300954	ENSP00000325917	proprotein convertase subtilisin/kexin type 4; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	0.433
PCSK4	SEC14L6	ENSP00000300954	ENSP00000385695	proprotein convertase subtilisin/kexin type 4; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex	SEC14-like 6 (S. cerevisiae)	0.467
PCSK5	PCSK6	ENSP00000446280	ENSP00000305056	proprotein convertase subtilisin/kexin type 5; Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins	proprotein convertase subtilisin/kexin type 6	0.930
PCSK5	PCSK7	ENSP00000446280	ENSP00000325917	proprotein convertase subtilisin/kexin type 5; Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	0.402
PCSK5	SEC14L6	ENSP00000446280	ENSP00000385695	proprotein convertase subtilisin/kexin type 5; Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins	SEC14-like 6 (S. cerevisiae)	0.467
PCSK6	PCSK5	ENSP00000305056	ENSP00000446280	proprotein convertase subtilisin/kexin type 6	proprotein convertase subtilisin/kexin type 5; Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins	0.930
PCSK6	PCSK7	ENSP00000305056	ENSP00000325917	proprotein convertase subtilisin/kexin type 6	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	0.400
PCSK6	SEC14L6	ENSP00000305056	ENSP00000385695	proprotein convertase subtilisin/kexin type 6	SEC14-like 6 (S. cerevisiae)	0.467
PCSK7	PCSK1	ENSP00000325917	ENSP00000308024	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	0.429
PCSK7	PCSK2	ENSP00000325917	ENSP00000262545	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	proprotein convertase subtilisin/kexin type 2	0.430
PCSK7	PCSK4	ENSP00000325917	ENSP00000300954	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	proprotein convertase subtilisin/kexin type 4; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex	0.433
PCSK7	PCSK5	ENSP00000325917	ENSP00000446280	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	proprotein convertase subtilisin/kexin type 5; Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins	0.402
PCSK7	PCSK6	ENSP00000325917	ENSP00000305056	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	proprotein convertase subtilisin/kexin type 6	0.400
PCSK7	SEC14L6	ENSP00000325917	ENSP00000385695	proprotein convertase subtilisin/kexin type 7; Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif	SEC14-like 6 (S. cerevisiae)	0.467
PLD1	SEC14L6	ENSP00000342793	ENSP00000385695	phospholipase D1, phosphatidylcholine-specific; Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity)	SEC14-like 6 (S. cerevisiae)	0.547

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