node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID4B | MAST4 | ENSP00000264183 | ENSP00000385727 | AT rich interactive domain 4B (RBP1-like) | microtubule associated serine/threonine kinase family member 4 | 0.576 |
DNAJC6 | MAST4 | ENSP00000378735 | ENSP00000385727 | DnaJ (Hsp40) homolog, subfamily C, member 6; Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (By similarity) | microtubule associated serine/threonine kinase family member 4 | 0.603 |
GALNS | MAST4 | ENSP00000268695 | ENSP00000385727 | galactosamine (N-acetyl)-6-sulfate sulfatase | microtubule associated serine/threonine kinase family member 4 | 0.545 |
MAST4 | ARID4B | ENSP00000385727 | ENSP00000264183 | microtubule associated serine/threonine kinase family member 4 | AT rich interactive domain 4B (RBP1-like) | 0.576 |
MAST4 | DNAJC6 | ENSP00000385727 | ENSP00000378735 | microtubule associated serine/threonine kinase family member 4 | DnaJ (Hsp40) homolog, subfamily C, member 6; Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (By similarity) | 0.603 |
MAST4 | GALNS | ENSP00000385727 | ENSP00000268695 | microtubule associated serine/threonine kinase family member 4 | galactosamine (N-acetyl)-6-sulfate sulfatase | 0.545 |
MAST4 | PTEN | ENSP00000385727 | ENSP00000361021 | microtubule associated serine/threonine kinase family member 4 | phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3- phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] | 0.739 |
MAST4 | SPG21 | ENSP00000385727 | ENSP00000204566 | microtubule associated serine/threonine kinase family member 4 | spastic paraplegia 21 (autosomal recessive, Mast syndrome); May play a role as a negative regulatory factor in CD4- dependent T-cell activation | 0.585 |
MAST4 | SRL | ENSP00000385727 | ENSP00000382518 | microtubule associated serine/threonine kinase family member 4 | sarcalumenin; May be involved in the regulation of calcium transport | 0.603 |
MAST4 | TENC1 | ENSP00000385727 | ENSP00000319756 | microtubule associated serine/threonine kinase family member 4 | tensin like C1 domain containing phosphatase (tensin 2) | 0.516 |
MAST4 | TNS3 | ENSP00000385727 | ENSP00000312143 | microtubule associated serine/threonine kinase family member 4 | tensin 3; May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity) | 0.516 |
MAST4 | TPTE | ENSP00000385727 | ENSP00000355208 | microtubule associated serine/threonine kinase family member 4 | transmembrane phosphatase with tensin homology; Could be involved in signal transduction | 0.712 |
MAST4 | TPTE2 | ENSP00000385727 | ENSP00000372437 | microtubule associated serine/threonine kinase family member 4 | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 | 0.684 |
PTEN | MAST4 | ENSP00000361021 | ENSP00000385727 | phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3- phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] | microtubule associated serine/threonine kinase family member 4 | 0.739 |
PTEN | SPG21 | ENSP00000361021 | ENSP00000204566 | phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3- phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] | spastic paraplegia 21 (autosomal recessive, Mast syndrome); May play a role as a negative regulatory factor in CD4- dependent T-cell activation | 0.416 |
SPG21 | MAST4 | ENSP00000204566 | ENSP00000385727 | spastic paraplegia 21 (autosomal recessive, Mast syndrome); May play a role as a negative regulatory factor in CD4- dependent T-cell activation | microtubule associated serine/threonine kinase family member 4 | 0.585 |
SPG21 | PTEN | ENSP00000204566 | ENSP00000361021 | spastic paraplegia 21 (autosomal recessive, Mast syndrome); May play a role as a negative regulatory factor in CD4- dependent T-cell activation | phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3- phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] | 0.416 |
SRL | MAST4 | ENSP00000382518 | ENSP00000385727 | sarcalumenin; May be involved in the regulation of calcium transport | microtubule associated serine/threonine kinase family member 4 | 0.603 |
SRL | TNS3 | ENSP00000382518 | ENSP00000312143 | sarcalumenin; May be involved in the regulation of calcium transport | tensin 3; May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity) | 0.464 |
TENC1 | MAST4 | ENSP00000319756 | ENSP00000385727 | tensin like C1 domain containing phosphatase (tensin 2) | microtubule associated serine/threonine kinase family member 4 | 0.516 |