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ACAD9 ACAD9 UBR3 UBR3 TMCC1 TMCC1 DNAJB8 DNAJB8 KBTBD12 KBTBD12 EEFSEC EEFSEC CCDC37 CCDC37 TTC39B TTC39B TMEM254 TMEM254 ABTB1 ABTB1 EEPD1 EEPD1
"KBTBD12" - kelch repeat and BTB in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KBTBD12kelch repeat and BTB (POZ) domain containing 12 (623 aa)    
Predicted Functional Partners:
TMEM254
transmembrane protein 254 (123 aa)
            score_image   0.700
CCDC37
coiled-coil domain containing 37 (611 aa)
            score_image   0.636
TMCC1
transmembrane and coiled-coil domain family 1 (653 aa)
            score_image   0.597
DNAJB8
DnaJ (Hsp40) homolog, subfamily B, member 8; Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins (232 aa)
            score_image   0.588
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1; May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes (478 aa)
            score_image   0.564
EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1 (569 aa)
            score_image   0.560
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA-specific; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP (596 aa)
            score_image   0.555
TTC39B
tetratricopeptide repeat domain 39B (682 aa)
            score_image   0.472
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative); E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity) (1888 aa)
            score_image   0.472
ACAD9
acyl-CoA dehydrogenase family, member 9; Has a dehydrogenase activity on palmitoyl-CoA (C16-0) and stearoyl-CoA (C18-0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. Has little activity on octanoyl-CoA (C8-0), butyryl-CoA (C4-0) or isovaleryl-CoA (5-0) (621 aa)
            score_image   0.443
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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