node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRIX1 | CEBPZ | ENSP00000338862 | ENSP00000234170 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | 0.988 |
BRIX1 | DDX24 | ENSP00000338862 | ENSP00000328690 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24; ATP-dependent RNA helicase (Potential) | 0.862 |
BRIX1 | EBNA1BP2 | ENSP00000338862 | ENSP00000407323 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | 0.999 |
BRIX1 | MKI67IP | ENSP00000338862 | ENSP00000285814 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.997 |
BRIX1 | NOC2L | ENSP00000338862 | ENSP00000317992 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter | 0.993 |
BRIX1 | NOP2 | ENSP00000338862 | ENSP00000382392 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.994 |
BRIX1 | PWP1 | ENSP00000338862 | ENSP00000387365 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | PWP1 homolog (S. cerevisiae); May play an important role in cell growth and/or transcription | 0.994 |
BRIX1 | RBM28 | ENSP00000338862 | ENSP00000223073 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes | 0.994 |
BRIX1 | RBM34 | ENSP00000338862 | ENSP00000386226 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | RNA binding motif protein 34 | 0.991 |
BRIX1 | WDR12 | ENSP00000338862 | ENSP00000261015 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.998 |
CEBPZ | BRIX1 | ENSP00000234170 | ENSP00000338862 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | 0.988 |
CEBPZ | DDX24 | ENSP00000234170 | ENSP00000328690 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24; ATP-dependent RNA helicase (Potential) | 0.993 |
CEBPZ | EBNA1BP2 | ENSP00000234170 | ENSP00000407323 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | 0.970 |
CEBPZ | MKI67IP | ENSP00000234170 | ENSP00000285814 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.971 |
CEBPZ | NOC2L | ENSP00000234170 | ENSP00000317992 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter | 0.998 |
CEBPZ | NOP2 | ENSP00000234170 | ENSP00000382392 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.986 |
CEBPZ | PWP1 | ENSP00000234170 | ENSP00000387365 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | PWP1 homolog (S. cerevisiae); May play an important role in cell growth and/or transcription | 0.778 |
CEBPZ | RBM28 | ENSP00000234170 | ENSP00000223073 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | RNA binding motif protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes | 0.997 |
CEBPZ | RBM34 | ENSP00000234170 | ENSP00000386226 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | RNA binding motif protein 34 | 0.975 |
CEBPZ | WDR12 | ENSP00000234170 | ENSP00000261015 | CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter | WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.987 |