SLC38A11 protein (Homo sapiens) - STRING network view

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SLC38A11

solute carrier family 38, member 11; Putative sodium-dependent amino acid/proton antiporter (By similarity) (406 aa)

Predicted Functional Partners:

ACLY

0.591

DPYD

0.557

SLC43A2

0.555

SLC36A3

0.519

SLC36A2

0.519

SLC36A4

0.519

SLC36A1

0.519

SLC6A14

0.462

GMPS

0.455

CPQ

0.410

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	DPYD	ENSP00000253792	ENSP00000359211	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	dihydropyrimidine dehydrogenase	0.940
ACLY	GMPS	ENSP00000253792	ENSP00000419851	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	0.414
ACLY	SLC36A1	ENSP00000253792	ENSP00000243389	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity)	0.591
ACLY	SLC36A2	ENSP00000253792	ENSP00000334223	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	solute carrier family 36 (proton/amino acid symporter), member 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity)	0.595
ACLY	SLC36A3	ENSP00000253792	ENSP00000366942	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	solute carrier family 36 (proton/amino acid symporter), member 3	0.591
ACLY	SLC36A4	ENSP00000253792	ENSP00000317382	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	solute carrier family 36 (proton/amino acid symporter), member 4; Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine. Inhibited by sarcosine	0.591
ACLY	SLC38A11	ENSP00000253792	ENSP00000386272	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	solute carrier family 38, member 11; Putative sodium-dependent amino acid/proton antiporter (By similarity)	0.591
CPQ	SLC38A11	ENSP00000220763	ENSP00000386272	carboxypeptidase Q; Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor	solute carrier family 38, member 11; Putative sodium-dependent amino acid/proton antiporter (By similarity)	0.410
DPYD	ACLY	ENSP00000359211	ENSP00000253792	dihydropyrimidine dehydrogenase	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	0.940
DPYD	GMPS	ENSP00000359211	ENSP00000419851	dihydropyrimidine dehydrogenase	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	0.886
DPYD	SLC36A1	ENSP00000359211	ENSP00000243389	dihydropyrimidine dehydrogenase	solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity)	0.557
DPYD	SLC36A2	ENSP00000359211	ENSP00000334223	dihydropyrimidine dehydrogenase	solute carrier family 36 (proton/amino acid symporter), member 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity)	0.557
DPYD	SLC36A3	ENSP00000359211	ENSP00000366942	dihydropyrimidine dehydrogenase	solute carrier family 36 (proton/amino acid symporter), member 3	0.557
DPYD	SLC36A4	ENSP00000359211	ENSP00000317382	dihydropyrimidine dehydrogenase	solute carrier family 36 (proton/amino acid symporter), member 4; Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine. Inhibited by sarcosine	0.557
DPYD	SLC38A11	ENSP00000359211	ENSP00000386272	dihydropyrimidine dehydrogenase	solute carrier family 38, member 11; Putative sodium-dependent amino acid/proton antiporter (By similarity)	0.557
GMPS	ACLY	ENSP00000419851	ENSP00000253792	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	0.414
GMPS	DPYD	ENSP00000419851	ENSP00000359211	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	dihydropyrimidine dehydrogenase	0.886
GMPS	SLC36A1	ENSP00000419851	ENSP00000243389	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	solute carrier family 36 (proton/amino acid symporter), member 1; Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity)	0.455
GMPS	SLC36A2	ENSP00000419851	ENSP00000334223	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	solute carrier family 36 (proton/amino acid symporter), member 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity)	0.455
GMPS	SLC36A3	ENSP00000419851	ENSP00000366942	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	solute carrier family 36 (proton/amino acid symporter), member 3	0.455

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