Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD16 | ANKRD22 | ENSP00000369434 | ENSP00000360998 | ankyrin repeat domain 16 | ankyrin repeat domain 22 | 0.471 |
ANKRD16 | ANKRD61 | ENSP00000369434 | ENSP00000386502 | ankyrin repeat domain 16 | ankyrin repeat domain 61 | 0.483 |
ANKRD16 | PHLPP1 | ENSP00000369434 | ENSP00000262719 | ankyrin repeat domain 16 | PH domain and leucine rich repeat protein phosphatase 1; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and suppression of tumor growth. Controls the phosphorylation of AKT2 and AKT3 more efficiently than that of AKT1. Dephosphorylation of PRKCA and PRKCB leads [...] | 0.403 |
ANKRD16 | PHLPP2 | ENSP00000369434 | ENSP00000348611 | ankyrin repeat domain 16 | PH domain and leucine rich repeat protein phosphatase 2; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradati [...] | 0.403 |
ANKRD16 | RFXANK | ENSP00000369434 | ENSP00000305071 | ankyrin repeat domain 16 | regulatory factor X-associated ankyrin-containing protein; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes | 0.507 |
ANKRD22 | ANKRD16 | ENSP00000360998 | ENSP00000369434 | ankyrin repeat domain 22 | ankyrin repeat domain 16 | 0.471 |
ANKRD22 | ANKRD39 | ENSP00000360998 | ENSP00000377170 | ankyrin repeat domain 22 | ankyrin repeat domain 39 | 0.442 |
ANKRD22 | ANKRD42 | ENSP00000360998 | ENSP00000377051 | ankyrin repeat domain 22 | ankyrin repeat domain 42 | 0.435 |
ANKRD22 | ANKRD61 | ENSP00000360998 | ENSP00000386502 | ankyrin repeat domain 22 | ankyrin repeat domain 61 | 0.448 |
ANKRD22 | CDKN2C | ENSP00000360998 | ENSP00000262662 | ankyrin repeat domain 22 | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB | 0.441 |
ANKRD22 | CDKN2D | ENSP00000360998 | ENSP00000337056 | ankyrin repeat domain 22 | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); Interacts strongly with CDK4 and CDK6 and inhibits them | 0.460 |
ANKRD22 | PHLPP1 | ENSP00000360998 | ENSP00000262719 | ankyrin repeat domain 22 | PH domain and leucine rich repeat protein phosphatase 1; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and suppression of tumor growth. Controls the phosphorylation of AKT2 and AKT3 more efficiently than that of AKT1. Dephosphorylation of PRKCA and PRKCB leads [...] | 0.403 |
ANKRD22 | PHLPP2 | ENSP00000360998 | ENSP00000348611 | ankyrin repeat domain 22 | PH domain and leucine rich repeat protein phosphatase 2; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradati [...] | 0.403 |
ANKRD22 | RFXANK | ENSP00000360998 | ENSP00000305071 | ankyrin repeat domain 22 | regulatory factor X-associated ankyrin-containing protein; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes | 0.461 |
ANKRD30BL | ANKRD42 | ENSP00000386398 | ENSP00000377051 | ankyrin repeat domain 30B-like | ankyrin repeat domain 42 | 0.506 |
ANKRD30BL | ANKRD61 | ENSP00000386398 | ENSP00000386502 | ankyrin repeat domain 30B-like | ankyrin repeat domain 61 | 0.525 |
ANKRD30BL | CDKN2C | ENSP00000386398 | ENSP00000262662 | ankyrin repeat domain 30B-like | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB | 0.449 |
ANKRD30BL | PHLPP1 | ENSP00000386398 | ENSP00000262719 | ankyrin repeat domain 30B-like | PH domain and leucine rich repeat protein phosphatase 1; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and suppression of tumor growth. Controls the phosphorylation of AKT2 and AKT3 more efficiently than that of AKT1. Dephosphorylation of PRKCA and PRKCB leads [...] | 0.403 |
ANKRD30BL | PHLPP2 | ENSP00000386398 | ENSP00000348611 | ankyrin repeat domain 30B-like | PH domain and leucine rich repeat protein phosphatase 2; Protein phosphatase that mediates dephosphorylation of ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser- 657’ of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser-473’ of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradati [...] | 0.403 |
ANKRD39 | ANKRD22 | ENSP00000377170 | ENSP00000360998 | ankyrin repeat domain 39 | ankyrin repeat domain 22 | 0.442 |
page 1 of 4