node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDK1 | GOLGA2 | ENSP00000378699 | ENSP00000416097 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | 0.993 |
CDK1 | GORASP1 | ENSP00000378699 | ENSP00000313869 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | golgi reassembly stacking protein 1, 65kDa; Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity- its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes | 0.997 |
CDK1 | RAB1A | ENSP00000378699 | ENSP00000387286 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | RAB1A, member RAS oncogene family; Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity | 0.984 |
CDK1 | UBC | ENSP00000378699 | ENSP00000344818 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | ubiquitin C | 0.999 |
GDI2 | RAB11B | ENSP00000369538 | ENSP00000333547 | GDP dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them | RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) | 0.994 |
GDI2 | RAB1A | ENSP00000369538 | ENSP00000387286 | GDP dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them | RAB1A, member RAS oncogene family; Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity | 0.998 |
GDI2 | RABGGTB | ENSP00000369538 | ENSP00000317473 | GDP dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them | Rab geranylgeranyltransferase, beta subunit; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively | 0.756 |
GDI2 | UBC | ENSP00000369538 | ENSP00000344818 | GDP dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them | ubiquitin C | 0.979 |
GOLGA2 | CDK1 | ENSP00000416097 | ENSP00000378699 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | 0.993 |
GOLGA2 | GOLGA5 | ENSP00000416097 | ENSP00000163416 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | golgin A5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport | 0.538 |
GOLGA2 | GORASP1 | ENSP00000416097 | ENSP00000313869 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | golgi reassembly stacking protein 1, 65kDa; Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity- its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes | 0.999 |
GOLGA2 | RAB1A | ENSP00000416097 | ENSP00000387286 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | RAB1A, member RAS oncogene family; Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity | 0.999 |
GOLGA2 | RABGGTB | ENSP00000416097 | ENSP00000317473 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | Rab geranylgeranyltransferase, beta subunit; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively | 0.448 |
GOLGA2 | STX5 | ENSP00000416097 | ENSP00000294179 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) | 0.909 |
GOLGA2 | UBC | ENSP00000416097 | ENSP00000344818 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | ubiquitin C | 0.730 |
GOLGA2 | USO1 | ENSP00000416097 | ENSP00000440586 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | USO1 vesicle docking protein homolog (yeast); General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity) | 0.999 |
GOLGA5 | GOLGA2 | ENSP00000163416 | ENSP00000416097 | golgin A5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | 0.538 |
GOLGA5 | GORASP1 | ENSP00000163416 | ENSP00000313869 | golgin A5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport | golgi reassembly stacking protein 1, 65kDa; Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity- its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes | 0.749 |
GOLGA5 | RAB1A | ENSP00000163416 | ENSP00000387286 | golgin A5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport | RAB1A, member RAS oncogene family; Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity | 0.982 |
GOLGA5 | STX5 | ENSP00000163416 | ENSP00000294179 | golgin A5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport | syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) | 0.510 |