node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERP27 | FKBP14 | ENSP00000266397 | ENSP00000222803 | endoplasmic reticulum protein 27 | FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis | 0.698 |
ERP27 | FKBP7 | ENSP00000266397 | ENSP00000413152 | endoplasmic reticulum protein 27 | FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis | 0.703 |
ERP27 | FOXRED2 | ENSP00000266397 | ENSP00000216187 | endoplasmic reticulum protein 27 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | 0.644 |
ERP27 | NENF | ENSP00000266397 | ENSP00000355955 | endoplasmic reticulum protein 27 | neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) | 0.637 |
ERP27 | PCYOX1 | ENSP00000266397 | ENSP00000387654 | endoplasmic reticulum protein 27 | prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.635 |
FKBP14 | ERP27 | ENSP00000222803 | ENSP00000266397 | FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis | endoplasmic reticulum protein 27 | 0.698 |
FKBP14 | FOXRED2 | ENSP00000222803 | ENSP00000216187 | FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | 0.633 |
FKBP14 | NENF | ENSP00000222803 | ENSP00000355955 | FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis | neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) | 0.635 |
FKBP14 | PCYOX1 | ENSP00000222803 | ENSP00000387654 | FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis | prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.648 |
FKBP7 | ERP27 | ENSP00000413152 | ENSP00000266397 | FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis | endoplasmic reticulum protein 27 | 0.703 |
FKBP7 | FOXRED2 | ENSP00000413152 | ENSP00000216187 | FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | 0.638 |
FKBP7 | NENF | ENSP00000413152 | ENSP00000355955 | FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis | neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) | 0.640 |
FKBP7 | PCYOX1 | ENSP00000413152 | ENSP00000387654 | FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis | prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.642 |
FOXRED2 | ERP27 | ENSP00000216187 | ENSP00000266397 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | endoplasmic reticulum protein 27 | 0.644 |
FOXRED2 | FKBP14 | ENSP00000216187 | ENSP00000222803 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis | 0.633 |
FOXRED2 | FKBP7 | ENSP00000216187 | ENSP00000413152 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis | 0.638 |
FOXRED2 | NENF | ENSP00000216187 | ENSP00000355955 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) | 0.659 |
FOXRED2 | PCYOX1 | ENSP00000216187 | ENSP00000387654 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.634 |
FOXRED2 | UBC | ENSP00000216187 | ENSP00000344818 | FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation | ubiquitin C | 0.483 |
LAMP1 | PCYOX1 | ENSP00000333298 | ENSP00000387654 | lysosomal-associated membrane protein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis | prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.751 |