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STRINGSTRING
ERP27 ERP27 NENF NENF FKBP14 FKBP14 FKBP7 FKBP7 FOXRED2 FOXRED2 PCYOX1 PCYOX1 LAMP1 LAMP1 PBLD PBLD UBC UBC NDUFV2 NDUFV2 SLC9A3R1 SLC9A3R1
"PCYOX1" - prenylcysteine oxidase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
PCYOX1prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (505 aa)    
Predicted Functional Partners:
LAMP1
lysosomal-associated membrane protein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis (417 aa)
            score_image   0.751
UBC
ubiquitin C (685 aa)
        score_image       0.740
FKBP14
FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis (211 aa)
            score_image   0.648
SLC9A3R1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli ( [...] (358 aa)
        score_image   score_image   0.645
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (249 aa)
        score_image       0.644
FKBP7
FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis (222 aa)
            score_image   0.642
NENF
neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) (172 aa)
            score_image   0.638
ERP27
endoplasmic reticulum protein 27 (273 aa)
            score_image   0.635
FOXRED2
FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (684 aa)
            score_image   0.634
PBLD
phenazine biosynthesis-like protein domain containing (288 aa)
            score_image   0.624
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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