node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL18A1 | RNF24 | ENSP00000347665 | ENSP00000388550 | collagen, type XVIII, alpha 1 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | 0.636 |
KIF1C | RNF24 | ENSP00000320821 | ENSP00000388550 | kinesin family member 1C; Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end- directed motility | ring finger protein 24; May play a role in TRPCs intracellular trafficking | 0.625 |
KIF1C | UBC | ENSP00000320821 | ENSP00000344818 | kinesin family member 1C; Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end- directed motility | ubiquitin C | 0.544 |
MUC5B | RNF24 | ENSP00000436812 | ENSP00000388550 | mucin 5B, oligomeric mucus/gel-forming | ring finger protein 24; May play a role in TRPCs intracellular trafficking | 0.649 |
RNF24 | COL18A1 | ENSP00000388550 | ENSP00000347665 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | collagen, type XVIII, alpha 1 | 0.636 |
RNF24 | KIF1C | ENSP00000388550 | ENSP00000320821 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | kinesin family member 1C; Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end- directed motility | 0.625 |
RNF24 | MUC5B | ENSP00000388550 | ENSP00000436812 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | mucin 5B, oligomeric mucus/gel-forming | 0.649 |
RNF24 | TRPC1 | ENSP00000388550 | ENSP00000273482 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion | 0.661 |
RNF24 | TRPC4 | ENSP00000388550 | ENSP00000369003 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | transient receptor potential cation channel, subfamily C, member 4 | 0.748 |
RNF24 | TRPC5 | ENSP00000388550 | ENSP00000262839 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | transient receptor potential cation channel, subfamily C, member 5; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion | 0.744 |
RNF24 | TRPC6 | ENSP00000388550 | ENSP00000340913 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | transient receptor potential cation channel, subfamily C, member 6; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion | 0.970 |
RNF24 | TRPM2 | ENSP00000388550 | ENSP00000300482 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | transient receptor potential cation channel, subfamily M, member 2; Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has [...] | 0.748 |
RNF24 | UBC | ENSP00000388550 | ENSP00000344818 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | ubiquitin C | 0.876 |
RNF24 | UQCRH | ENSP00000388550 | ENSP00000309565 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | ubiquinol-cytochrome c reductase hinge protein; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 | 0.624 |
TRPC1 | RNF24 | ENSP00000273482 | ENSP00000388550 | transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion | ring finger protein 24; May play a role in TRPCs intracellular trafficking | 0.661 |
TRPC1 | TRPC4 | ENSP00000273482 | ENSP00000369003 | transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion | transient receptor potential cation channel, subfamily C, member 4 | 0.981 |
TRPC1 | TRPC5 | ENSP00000273482 | ENSP00000262839 | transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion | transient receptor potential cation channel, subfamily C, member 5; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion | 0.991 |
TRPC1 | TRPC6 | ENSP00000273482 | ENSP00000340913 | transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion | transient receptor potential cation channel, subfamily C, member 6; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion | 0.961 |
TRPC4 | RNF24 | ENSP00000369003 | ENSP00000388550 | transient receptor potential cation channel, subfamily C, member 4 | ring finger protein 24; May play a role in TRPCs intracellular trafficking | 0.748 |
TRPC4 | TRPC1 | ENSP00000369003 | ENSP00000273482 | transient receptor potential cation channel, subfamily C, member 4 | transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion | 0.981 |