RWDD4 protein (Homo sapiens) - STRING network view

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RWDD4

RWD domain containing 4 (188 aa)

Predicted Functional Partners:

DRG1

0.949

DRG2

0.940

GCN1L1

0.862

LARP7

0.660

SSB

0.660

BTF3

0.644

ESF1

0.518

HAUS6

0.503

UBC

0.501

EBNA1BP2

0.495

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTF3	RWDD4	ENSP00000369965	ENSP00000388920	basic transcription factor 3; General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription	RWD domain containing 4	0.644
BTF3	UBC	ENSP00000369965	ENSP00000344818	basic transcription factor 3; General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription	ubiquitin C	0.947
DRG1	DRG2	ENSP00000329715	ENSP00000225729	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death	0.875
DRG1	GCN1L1	ENSP00000329715	ENSP00000300648	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.570
DRG1	LARP7	ENSP00000329715	ENSP00000314311	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	La ribonucleoprotein domain family, member 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation	0.416
DRG1	RWDD4	ENSP00000329715	ENSP00000388920	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	RWD domain containing 4	0.949
DRG1	SSB	ENSP00000329715	ENSP00000260956	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	Sjogren syndrome antigen B (autoantigen La); Binds to the 3’ poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation	0.426
DRG1	UBC	ENSP00000329715	ENSP00000344818	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	ubiquitin C	0.988
DRG2	DRG1	ENSP00000225729	ENSP00000329715	developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death	developmentally regulated GTP binding protein 1; Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest	0.875
DRG2	GCN1L1	ENSP00000225729	ENSP00000300648	developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.966
DRG2	RWDD4	ENSP00000225729	ENSP00000388920	developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death	RWD domain containing 4	0.940
DRG2	UBC	ENSP00000225729	ENSP00000344818	developmentally regulated GTP binding protein 2; May play a role in cell proliferation, differentiation and death	ubiquitin C	0.957
EBNA1BP2	ESF1	ENSP00000407323	ENSP00000202816	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	0.873
EBNA1BP2	LARP7	ENSP00000407323	ENSP00000314311	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	La ribonucleoprotein domain family, member 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation	0.866
EBNA1BP2	RWDD4	ENSP00000407323	ENSP00000388920	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	RWD domain containing 4	0.495
EBNA1BP2	SSB	ENSP00000407323	ENSP00000260956	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	Sjogren syndrome antigen B (autoantigen La); Binds to the 3’ poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation	0.862
EBNA1BP2	UBC	ENSP00000407323	ENSP00000344818	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	ubiquitin C	0.891
ESF1	EBNA1BP2	ENSP00000202816	ENSP00000407323	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity)	0.873
ESF1	LARP7	ENSP00000202816	ENSP00000314311	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	La ribonucleoprotein domain family, member 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation	0.742
ESF1	RWDD4	ENSP00000202816	ENSP00000388920	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	RWD domain containing 4	0.518

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