Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
|||||
 | TDRD12 | tudor domain containing 12 (395 aa) | ||||||||||||
Predicted Functional Partners:
| ||||||||||||||
 | DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (1220 aa) |
 |
|
|
|
0.841 | |||||||
 | DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 (851 aa) |
|
|
|
0.764 | ||||||||
 | DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors (882 aa) |
|
|
|
0.721 | ||||||||
 | NOP2 | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase (808 aa) |
|
|
|
0.691 | ||||||||
 | NSUN6 | NOP2/Sun domain family, member 6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) (469 aa) |
|
|
|
0.691 | ||||||||
 | YTHDC2 | YTH domain containing 2 (1430 aa) |
|
|
|
0.687 | ||||||||
 | RPF2 | ribosome production factor 2 homolog (S. cerevisiae) (306 aa) |
|
|
|
0.683 | ||||||||
 | DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like (1706 aa) |
|
|
|
0.675 | ||||||||
 | DDX47 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; Involved in apoptosis. May have a role in rRNA processing and mRNA splicing. Associates with pre-rRNA precursors (455 aa) |
|
|
|
0.642 | ||||||||
 | DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (540 aa) |
|
|
|
0.642 | ||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
Share
