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RUVBL1 RUVBL1 INO80E INO80E INO80C INO80C ACTL6A ACTL6A NFRKB NFRKB RUVBL2 RUVBL2 ACTR5 ACTR5 INO80B INO80B INO80 INO80 MCRS1 MCRS1 ACTR8 ACTR8
"INO80C" - INO80 complex subunit C in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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INO80CINO80 complex subunit C; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair (228 aa)    
Predicted Functional Partners:
INO80
INO80 homolog (S. cerevisiae); DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed-20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segreg [...] (1556 aa)
        score_image score_image score_image   0.999
INO80E
INO80 complex subunit E; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair (244 aa)
        score_image score_image score_image   0.992
ACTR5
ARP5 actin-related protein 5 homolog (yeast); Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair (607 aa)
        score_image score_image score_image   0.992
ACTR8
ARP8 actin-related protein 8 homolog (yeast); Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (624 aa)
        score_image score_image score_image   0.985
ACTL6A
actin-like 6A; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as [...] (429 aa)
        score_image score_image score_image   0.979
RUVBL2
RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5’ to 3’) activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity (463 aa)
        score_image score_image score_image   0.976
RUVBL1
RuvB-like 1 (E. coli); May be able to bind plasminogen at cell surface and enhance plasminogen activation (456 aa)
        score_image score_image score_image   0.975
INO80B
INO80 complex subunit B; Induces growth and cell cycle arrests at the G1 phase of the cell cycle (356 aa)
        score_image score_image score_image   0.973
MCRS1
microspherule protein 1; Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (475 aa)
        score_image score_image score_image   0.960
NFRKB
nuclear factor related to kappaB binding protein; Binds to the DNA consensus sequence 5’-GGGGAATCTCC-3’ (1324 aa)
        score_image score_image score_image   0.955
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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