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STRINGSTRING
NU NU IQCE IQCE PSMA1 PSMA1 KIF1A KIF1A MTUS2 MTUS2 NUBPL NUBPL MAPRE2 MAPRE2 KIF2C KIF2C MAPRE1 MAPRE1 KAT5 KAT5 KIF2A KIF2A
"MTUS2" - microtubule associated tumor suppressor candidate 2 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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query proteins and first shell of interactors
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second shell of interactors
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MTUS2microtubule associated tumor suppressor candidate 2; Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip (1379 aa)    
Predicted Functional Partners:
MAPRE2
microtubule-associated protein, RP/EB family, member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity) (327 aa)
        score_image   score_image   0.921
MAPRE1
microtubule-associated protein, RP/EB family, member 1; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (268 aa)
        score_image   score_image   0.920
KIF2C
kinesin family member 2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (725 aa)
        score_image   score_image   0.783
NUBPL
nucleotide binding protein-like; Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits (319 aa)
        score_image       0.692
KIF1A
kinesin family member 1A (1690 aa)
        score_image       0.691
KAT5
K(lysine) acetyltransferase 5 (546 aa)
        score_image   score_image   0.573
IQCE
IQ motif containing E (695 aa)
        score_image       0.572
KIF2A
kinesin heavy chain member 2A; Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity (744 aa)
            score_image   0.531
NU
proteasome subunit alpha type-1 isoform 3 ; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) (164 aa)
        score_image       0.507
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity) (269 aa)
        score_image       0.507
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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