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BMP2 BMP2 FSTL1 FSTL1 FST FST DLX2 DLX2 TGFB1 TGFB1 DIP2A DIP2A UBC UBC ACACB ACACB ACACA ACACA HADHA HADHA EHHADH EHHADH
"DIP2A" - DIP2 disco-interacting protein 2 homolog A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila); May provide positional cues for axon pathfinding and patterning in the central nervous system (1571 aa)    
Predicted Functional Partners:
FSTL1
follistatin-like 1; May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity) (308 aa)
        score_image   score_image   0.777
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.760
FST
follistatin; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH) (344 aa)
        score_image   score_image   0.673
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa)
score_image           score_image   0.614
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa)
score_image           score_image   0.614
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
score_image           score_image   0.599
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
score_image           score_image   0.599
TGFB1
transforming growth factor, beta 1; Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (390 aa)
        score_image   score_image   0.588
DLX2
distal-less homeobox 2; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis (328 aa)
        score_image       0.576
BMP2
bone morphogenetic protein 2; Induces cartilage and bone formation (396 aa)
        score_image   score_image   0.571
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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