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STRINGSTRING
YARS YARS SLC20A1 SLC20A1 SLC26A3 SLC26A3 SLC20A2 SLC20A2 SLC13A2 SLC13A2 SLC15A5 SLC15A5 MAPK8IP2 MAPK8IP2 PMS2 PMS2 PPIB PPIB SLC12A9 SLC12A9 SLC26A2 SLC26A2
"SLC13A2" - solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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Predicted Interactions
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protein homology
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SLC13A2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2; Cotransport of sodium ions and dicarboxylates such as succinate and citrate (641 aa)    
Predicted Functional Partners:
PPIB
peptidylprolyl isomerase B (cyclophilin B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (216 aa)
             score_image   0.893
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae); Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2- MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade [...] (862 aa)
             score_image   0.800
SLC15A5
solute carrier family 15, member 5; Proton oligopeptide cotransporter (Potential) (579 aa)
             score_image   0.725
SLC26A2
solute carrier family 26 (sulfate transporter), member 2; Sulfate transporter. May play a role in endochondral bone formation (739 aa)
             score_image   0.698
SLC26A3
solute carrier family 26, member 3; Chloride/bicarbonate exchanger. Mediates the efficient absorbtion of chloride ions in the colon, participating in fluid homeostasis (764 aa)
             score_image   0.647
SLC20A1
solute carrier family 20 (phosphate transporter), member 1; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus [...] (679 aa)
       score_image score_image   score_image   0.638
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity) (823 aa)
             score_image   0.632
SLC20A2
solute carrier family 20 (phosphate transporter), member 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Fun [...] (652 aa)
       score_image score_image   score_image   0.622
SLC12A9
solute carrier family 12 (potassium/chloride transporters), member 9 (914 aa)
             score_image   0.548
YARS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) (528 aa)
         score_image   score_image   0.547
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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