TOR1AIP1 protein (Homo sapiens) - STRING network view

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TOR1AIP1

torsin A interacting protein 1 (583 aa)

Predicted Functional Partners:

TOR1A

0.988

RIF1

0.904

UBC

0.849

LMNA

0.816

TOR3A

0.812

TOR2A

0.684

LMNB1

0.682

NIT2

0.648

S100A16

0.644

NUP50

0.644

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LMNA	LMNB1	ENSP00000357283	ENSP00000261366	lamin A/C	lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin	0.992
LMNA	TOR1A	ENSP00000357283	ENSP00000345719	lamin A/C	torsin family 1, member A (torsin A); May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. In the nucleus, displaces the nuclear membrane proteins SUN2, SYNE2 and SYNE3, leaving nuclear pores and SUN1 unchanged	0.715
LMNA	TOR1AIP1	ENSP00000357283	ENSP00000393292	lamin A/C	torsin A interacting protein 1	0.816
LMNA	UBC	ENSP00000357283	ENSP00000344818	lamin A/C	ubiquitin C	0.984
LMNB1	LMNA	ENSP00000261366	ENSP00000357283	lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin	lamin A/C	0.992
LMNB1	TOR1AIP1	ENSP00000261366	ENSP00000393292	lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin	torsin A interacting protein 1	0.682
LMNB1	UBC	ENSP00000261366	ENSP00000344818	lamin B1; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin	ubiquitin C	0.971
NIT2	TOR1AIP1	ENSP00000377696	ENSP00000393292	nitrilase family, member 2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle	torsin A interacting protein 1	0.648
NIT2	UBC	ENSP00000377696	ENSP00000344818	nitrilase family, member 2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle	ubiquitin C	0.675
NUP50	TOR1AIP1	ENSP00000345895	ENSP00000393292	nucleoporin 50kDa; Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha-beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B	torsin A interacting protein 1	0.644
NUP50	UBC	ENSP00000345895	ENSP00000344818	nucleoporin 50kDa; Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha-beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B	ubiquitin C	0.849
RIF1	TOR1AIP1	ENSP00000243326	ENSP00000393292	RAP1 interacting factor homolog (yeast)	torsin A interacting protein 1	0.904
RIF1	UBC	ENSP00000243326	ENSP00000344818	RAP1 interacting factor homolog (yeast)	ubiquitin C	0.795
S100A16	TOR1AIP1	ENSP00000357692	ENSP00000393292	S100 calcium binding protein A16; Calcium-binding protein. Binds one calcium ion per monomer	torsin A interacting protein 1	0.644
S100A16	UBC	ENSP00000357692	ENSP00000344818	S100 calcium binding protein A16; Calcium-binding protein. Binds one calcium ion per monomer	ubiquitin C	0.483
TOR1A	LMNA	ENSP00000345719	ENSP00000357283	torsin family 1, member A (torsin A); May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. In the nucleus, displaces the nuclear membrane proteins SUN2, SYNE2 and SYNE3, leaving nuclear pores and SUN1 unchanged	lamin A/C	0.715
TOR1A	TOR1AIP1	ENSP00000345719	ENSP00000393292	torsin family 1, member A (torsin A); May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. In the nucleus, displaces the nuclear membrane proteins SUN2, SYNE2 and SYNE3, leaving nuclear pores and SUN1 unchanged	torsin A interacting protein 1	0.988
TOR1A	TOR3A	ENSP00000345719	ENSP00000356599	torsin family 1, member A (torsin A); May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. In the nucleus, displaces the nuclear membrane proteins SUN2, SYNE2 and SYNE3, leaving nuclear pores and SUN1 unchanged	torsin family 3, member A	0.588
TOR1A	UBC	ENSP00000345719	ENSP00000344818	torsin family 1, member A (torsin A); May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. In the nucleus, displaces the nuclear membrane proteins SUN2, SYNE2 and SYNE3, leaving nuclear pores and SUN1 unchanged	ubiquitin C	0.496
TOR1AIP1	LMNA	ENSP00000393292	ENSP00000357283	torsin A interacting protein 1	lamin A/C	0.816

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