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SPP2 SPP2 RGMA RGMA AHSG AHSG BMPR1B BMPR1B BMP2 BMP2 BMPR2 BMPR2 BAMBI BAMBI BMPR1A BMPR1A RGMB RGMB BMP4 BMP4 BMP6 BMP6
"AHSG" - alpha-2-HS-glycoprotein in Homo sapiens
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protein of unknown 3D structure
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AHSGalpha-2-HS-glycoprotein; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions (367 aa)    
Predicted Functional Partners:
BMP2
bone morphogenetic protein 2; Induces cartilage and bone formation (396 aa)
          score_image score_image   0.913
RGMA
RGM domain family, member A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivati [...] (458 aa)
          score_image score_image   0.902
BMP4
bone morphogenetic protein 4; Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity) (408 aa)
          score_image score_image   0.901
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis); Negatively regulates TGF-beta signaling (By similarity) (260 aa)
          score_image     0.900
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase); On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs (1038 aa)
          score_image     0.900
RGMB
RGM domain family, member B; Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth (478 aa)
          score_image     0.900
BMP6
bone morphogenetic protein 6; Induces cartilage and bone formation (513 aa)
          score_image     0.900
BMPR1B
bone morphogenetic protein receptor, type IB; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5 (502 aa)
          score_image     0.900
BMPR1A
bone morphogenetic protein receptor, type IA; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4 (532 aa)
          score_image     0.900
SPP2
secreted phosphoprotein 2, 24kDa; Could coordinate an aspect of bone turnover (By similarity) (211 aa)
      score_image     score_image   0.847
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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