BZW1 protein (Homo sapiens) - STRING network view

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Score

BZW1

basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly (451 aa)

Predicted Functional Partners:

UBC

0.943

EIF4G1

0.781

EIF4G3

0.776

CDC5L

0.729

HNRNPA1L2

0.644

KCTD18

0.637

BZW2

0.616

TYW5

0.615

LZTFL1

0.613

LDHA

0.551

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BZW1	BZW2	ENSP00000394316	ENSP00000258761	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	0.616
BZW1	CDC5L	ENSP00000394316	ENSP00000360532	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing	0.729
BZW1	EIF4G1	ENSP00000394316	ENSP00000338020	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	eukaryotic translation initiation factor 4 gamma, 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5’-terminal secondary structure and recruitment of mRNA to the ribosome	0.781
BZW1	EIF4G3	ENSP00000394316	ENSP00000364073	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	eukaryotic translation initiation factor 4 gamma, 3; Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5’-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1	0.776
BZW1	HNRNPA1L2	ENSP00000394316	ENSP00000341285	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	heterogeneous nuclear ribonucleoprotein A1-like 2; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity)	0.644
BZW1	KCTD18	ENSP00000394316	ENSP00000352941	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	potassium channel tetramerisation domain containing 18	0.637
BZW1	LDHA	ENSP00000394316	ENSP00000445175	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	lactate dehydrogenase A	0.551
BZW1	LZTFL1	ENSP00000394316	ENSP00000296135	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	leucine zipper transcription factor-like 1	0.613
BZW1	TYW5	ENSP00000394316	ENSP00000346627	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	tRNA-yW synthesizing protein 5; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW). OHyW being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes	0.615
BZW1	UBC	ENSP00000394316	ENSP00000344818	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	ubiquitin C	0.943
BZW2	BZW1	ENSP00000258761	ENSP00000394316	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	0.616
BZW2	EIF4G1	ENSP00000258761	ENSP00000338020	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	eukaryotic translation initiation factor 4 gamma, 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5’-terminal secondary structure and recruitment of mRNA to the ribosome	0.776
BZW2	EIF4G3	ENSP00000258761	ENSP00000364073	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	eukaryotic translation initiation factor 4 gamma, 3; Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5’-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1	0.776
BZW2	KCTD18	ENSP00000258761	ENSP00000352941	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	potassium channel tetramerisation domain containing 18	0.485
BZW2	LZTFL1	ENSP00000258761	ENSP00000296135	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	leucine zipper transcription factor-like 1	0.571
BZW2	TYW5	ENSP00000258761	ENSP00000346627	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	tRNA-yW synthesizing protein 5; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW). OHyW being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes	0.487
BZW2	UBC	ENSP00000258761	ENSP00000344818	basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity)	ubiquitin C	0.938
CDC5L	BZW1	ENSP00000360532	ENSP00000394316	CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing	basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly	0.729
CDC5L	HNRNPA1L2	ENSP00000360532	ENSP00000341285	CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing	heterogeneous nuclear ribonucleoprotein A1-like 2; Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (By similarity)	0.515
CDC5L	UBC	ENSP00000360532	ENSP00000344818	CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing	ubiquitin C	0.740

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