ZNF200 protein (Homo sapiens) - STRING network view

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ZNF200

zinc finger protein 200; Could have a role in spermatogenesis (395 aa)

Predicted Functional Partners:

OR1F1

0.755

MEFV

0.683

SLC22A3

0.606

EHMT2

0.603

SLC22A2

0.587

ZMYM2

0.583

FOSB

0.551

XRN1

0.543

SUV39H1

0.506

MFSD7

0.506

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHMT2	FOSB	ENSP00000364687	ENSP00000245919	euchromatic histone-lysine N-methyltransferase 2	FBJ murine osteosarcoma viral oncogene homolog B; FosB interacts with Jun proteins enhancing their DNA binding activity	0.947
EHMT2	SLC22A2	ENSP00000364687	ENSP00000355920	euchromatic histone-lysine N-methyltransferase 2	solute carrier family 22 (organic cation transporter), member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited b [...]	0.562
EHMT2	SLC22A3	ENSP00000364687	ENSP00000275300	euchromatic histone-lysine N-methyltransferase 2	solute carrier family 22 (extraneuronal monoamine transporter), member 3; Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain	0.606
EHMT2	ZNF200	ENSP00000364687	ENSP00000395723	euchromatic histone-lysine N-methyltransferase 2	zinc finger protein 200; Could have a role in spermatogenesis	0.603
FOSB	EHMT2	ENSP00000245919	ENSP00000364687	FBJ murine osteosarcoma viral oncogene homolog B; FosB interacts with Jun proteins enhancing their DNA binding activity	euchromatic histone-lysine N-methyltransferase 2	0.947
FOSB	ZNF200	ENSP00000245919	ENSP00000395723	FBJ murine osteosarcoma viral oncogene homolog B; FosB interacts with Jun proteins enhancing their DNA binding activity	zinc finger protein 200; Could have a role in spermatogenesis	0.551
MEFV	OR1F1	ENSP00000219596	ENSP00000305424	Mediterranean fever; Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization	olfactory receptor, family 1, subfamily F, member 1; Odorant receptor (Potential)	0.758
MEFV	ZNF200	ENSP00000219596	ENSP00000395723	Mediterranean fever; Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization	zinc finger protein 200; Could have a role in spermatogenesis	0.683
MFSD7	ZNF200	ENSP00000320234	ENSP00000395723	major facilitator superfamily domain containing 7	zinc finger protein 200; Could have a role in spermatogenesis	0.506
OR1F1	MEFV	ENSP00000305424	ENSP00000219596	olfactory receptor, family 1, subfamily F, member 1; Odorant receptor (Potential)	Mediterranean fever; Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization	0.758
OR1F1	ZNF200	ENSP00000305424	ENSP00000395723	olfactory receptor, family 1, subfamily F, member 1; Odorant receptor (Potential)	zinc finger protein 200; Could have a role in spermatogenesis	0.755
SLC22A2	EHMT2	ENSP00000355920	ENSP00000364687	solute carrier family 22 (organic cation transporter), member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited b [...]	euchromatic histone-lysine N-methyltransferase 2	0.562
SLC22A2	ZNF200	ENSP00000355920	ENSP00000395723	solute carrier family 22 (organic cation transporter), member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited b [...]	zinc finger protein 200; Could have a role in spermatogenesis	0.587
SLC22A3	EHMT2	ENSP00000275300	ENSP00000364687	solute carrier family 22 (extraneuronal monoamine transporter), member 3; Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain	euchromatic histone-lysine N-methyltransferase 2	0.606
SLC22A3	ZNF200	ENSP00000275300	ENSP00000395723	solute carrier family 22 (extraneuronal monoamine transporter), member 3; Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain	zinc finger protein 200; Could have a role in spermatogenesis	0.606
SUV39H1	ZNF200	ENSP00000365877	ENSP00000395723	suppressor of variegation 3-9 homolog 1 (Drosophila); Histone methyltransferase that specifically trimethylates ’Lys-9’ of histone H3 using monomethylated H3 ’Lys- 9’ as substrate. Also weakly methylates histone H1 (in vitro). H3 ’Lys-9’ trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 ’Lys-9’ trimethylation is [...]	zinc finger protein 200; Could have a role in spermatogenesis	0.506
XRN1	ZNF200	ENSP00000264951	ENSP00000395723	5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS)	zinc finger protein 200; Could have a role in spermatogenesis	0.543
ZMYM2	ZNF200	ENSP00000372322	ENSP00000395723	zinc finger, MYM-type 2	zinc finger protein 200; Could have a role in spermatogenesis	0.583
ZNF200	EHMT2	ENSP00000395723	ENSP00000364687	zinc finger protein 200; Could have a role in spermatogenesis	euchromatic histone-lysine N-methyltransferase 2	0.603
ZNF200	FOSB	ENSP00000395723	ENSP00000245919	zinc finger protein 200; Could have a role in spermatogenesis	FBJ murine osteosarcoma viral oncogene homolog B; FosB interacts with Jun proteins enhancing their DNA binding activity	0.551

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