| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BOP1 | EBNA1BP2 | ENSP00000304151 | ENSP00000407323 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | 0.967 |
| BOP1 | EIF6 | ENSP00000304151 | ENSP00000363559 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity | 0.834 |
| BOP1 | FTSJ3 | ENSP00000304151 | ENSP00000396673 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.944 |
| BOP1 | GNL3 | ENSP00000304151 | ENSP00000395772 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) | 0.996 |
| BOP1 | GTPBP4 | ENSP00000304151 | ENSP00000354040 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | 0.986 |
| BOP1 | MKI67IP | ENSP00000304151 | ENSP00000285814 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.959 |
| BOP1 | NOP2 | ENSP00000304151 | ENSP00000382392 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.996 |
| BOP1 | PES1 | ENSP00000304151 | ENSP00000346725 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.999 |
| BOP1 | RRS1 | ENSP00000304151 | ENSP00000322396 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) | 0.896 |
| EBNA1BP2 | BOP1 | ENSP00000407323 | ENSP00000304151 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.967 |
| EBNA1BP2 | EIF6 | ENSP00000407323 | ENSP00000363559 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity | 0.950 |
| EBNA1BP2 | ENSG00000204775 | ENSP00000407323 | ENSP00000366629 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | KM-PA-2 protein; Uncharacterized protein | 0.964 |
| EBNA1BP2 | FTSJ3 | ENSP00000407323 | ENSP00000396673 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | FtsJ homolog 3 (E. coli); Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation | 0.999 |
| EBNA1BP2 | GNL3 | ENSP00000407323 | ENSP00000395772 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | guanine nucleotide binding protein-like 3 (nucleolar); May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity) | 0.998 |
| EBNA1BP2 | GTPBP4 | ENSP00000407323 | ENSP00000354040 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (By similarity) | 0.976 |
| EBNA1BP2 | MKI67IP | ENSP00000407323 | ENSP00000285814 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.993 |
| EBNA1BP2 | NOP2 | ENSP00000407323 | ENSP00000382392 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.999 |
| EBNA1BP2 | PES1 | ENSP00000407323 | ENSP00000346725 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.994 |
| EBNA1BP2 | RRS1 | ENSP00000407323 | ENSP00000322396 | EBNA1 binding protein 2; Required for the processing of the 27S pre-rRNA (By similarity) | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); Involved in ribosome biogenesis (By similarity) | 0.999 |
| EIF6 | BOP1 | ENSP00000363559 | ENSP00000304151 | eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.834 |
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