| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCND1 | UBC | ENSP00000227507 | ENSP00000344818 | cyclin D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate [...] | ubiquitin C | 0.999 |
| CCND1 | URGCP | ENSP00000227507 | ENSP00000396918 | cyclin D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate [...] | upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer | 0.835 |
| FAM188A | UBC | ENSP00000277632 | ENSP00000344818 | family with sequence similarity 188, member A | ubiquitin C | 0.795 |
| FAM188A | URGCP | ENSP00000277632 | ENSP00000396918 | family with sequence similarity 188, member A | upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer | 0.662 |
| NDUFAF7 | SAMD11 | ENSP00000002125 | ENSP00000342313 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | 0.412 |
| NDUFAF7 | TAMM41 | ENSP00000002125 | ENSP00000273037 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | 0.722 |
| NDUFAF7 | TAS2R13 | ENSP00000002125 | ENSP00000375095 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | taste receptor, type 2, member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 | 0.406 |
| NDUFAF7 | URGCP | ENSP00000002125 | ENSP00000396918 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer | 0.412 |
| NDUFAF7 | ZNF598 | ENSP00000002125 | ENSP00000411409 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | zinc finger protein 598 | 0.408 |
| SAMD11 | NDUFAF7 | ENSP00000342313 | ENSP00000002125 | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | 0.412 |
| SAMD11 | TAMM41 | ENSP00000342313 | ENSP00000273037 | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | 0.457 |
| SAMD11 | TAS2R13 | ENSP00000342313 | ENSP00000375095 | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | taste receptor, type 2, member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 | 0.453 |
| SAMD11 | URGCP | ENSP00000342313 | ENSP00000396918 | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer | 0.459 |
| SAMD11 | ZNF598 | ENSP00000342313 | ENSP00000411409 | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | zinc finger protein 598 | 0.459 |
| TAMM41 | NDUFAF7 | ENSP00000273037 | ENSP00000002125 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | 0.722 |
| TAMM41 | SAMD11 | ENSP00000273037 | ENSP00000342313 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) | 0.457 |
| TAMM41 | TAS2R13 | ENSP00000273037 | ENSP00000375095 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | taste receptor, type 2, member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 | 0.450 |
| TAMM41 | URGCP | ENSP00000273037 | ENSP00000396918 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer | 0.457 |
| TAMM41 | ZNF598 | ENSP00000273037 | ENSP00000411409 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | zinc finger protein 598 | 0.457 |
| TAS2R13 | NDUFAF7 | ENSP00000375095 | ENSP00000002125 | taste receptor, type 2, member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) | 0.406 |
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