node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGL | AMY2A | ENSP00000294724 | ENSP00000397582 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | amylase, alpha 2A (pancreatic) | 0.910 |
AGL | GBE1 | ENSP00000294724 | ENSP00000410833 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | 0.996 |
AGL | PYGB | ENSP00000294724 | ENSP00000216962 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.998 |
AGL | PYGL | ENSP00000294724 | ENSP00000216392 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.998 |
AGL | SI | ENSP00000294724 | ENSP00000264382 | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides | 0.905 |
AMY2A | AGL | ENSP00000397582 | ENSP00000294724 | amylase, alpha 2A (pancreatic) | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.910 |
AMY2A | ENO1 | ENSP00000397582 | ENSP00000234590 | amylase, alpha 2A (pancreatic) | enolase 1, (alpha) | 0.564 |
AMY2A | GBE1 | ENSP00000397582 | ENSP00000410833 | amylase, alpha 2A (pancreatic) | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | 0.960 |
AMY2A | GP2 | ENSP00000397582 | ENSP00000370767 | amylase, alpha 2A (pancreatic) | glycoprotein 2 (zymogen granule membrane) | 0.576 |
AMY2A | MGAM | ENSP00000397582 | ENSP00000447378 | amylase, alpha 2A (pancreatic) | maltase-glucoamylase (alpha-glucosidase); May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing | 0.929 |
AMY2A | PNLIP | ENSP00000397582 | ENSP00000358223 | amylase, alpha 2A (pancreatic) | pancreatic lipase | 0.566 |
AMY2A | PYGB | ENSP00000397582 | ENSP00000216962 | amylase, alpha 2A (pancreatic) | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.953 |
AMY2A | PYGL | ENSP00000397582 | ENSP00000216392 | amylase, alpha 2A (pancreatic) | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.953 |
AMY2A | SI | ENSP00000397582 | ENSP00000264382 | amylase, alpha 2A (pancreatic) | sucrase-isomaltase (alpha-glucosidase); Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides | 0.924 |
AMY2A | TSHB | ENSP00000397582 | ENSP00000256592 | amylase, alpha 2A (pancreatic) | thyroid stimulating hormone, beta; Indispensable for the control of thyroid structure and metabolism | 0.588 |
ENO1 | AMY2A | ENSP00000234590 | ENSP00000397582 | enolase 1, (alpha) | amylase, alpha 2A (pancreatic) | 0.564 |
ENO1 | GBE1 | ENSP00000234590 | ENSP00000410833 | enolase 1, (alpha) | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | 0.466 |
ENO1 | PYGB | ENSP00000234590 | ENSP00000216962 | enolase 1, (alpha) | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.794 |
ENO1 | PYGL | ENSP00000234590 | ENSP00000216392 | enolase 1, (alpha) | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.807 |
GBE1 | AGL | ENSP00000410833 | ENSP00000294724 | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.996 |