TMA7 protein (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Predicted Interactions

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[Homology]

Score

TMA7

translational machinery associated 7 homolog (S. cerevisiae) (64 aa)

Predicted Functional Partners:

COMMD4

0.584

UBE2D4

0.504

SEC11A

0.418

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COMMD4	TMA7	ENSP00000267935	ENSP00000397843	COMM domain containing 4; Down-regulates activation of NF-kappa-B	translational machinery associated 7 homolog (S. cerevisiae)	0.584
COMMD4	UBE2D4	ENSP00000267935	ENSP00000222402	COMM domain containing 4; Down-regulates activation of NF-kappa-B	ubiquitin-conjugating enzyme E2D 4 (putative); Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer ’Lys-11’ and ’Lys-48’-linked polyubiquitination	0.501
SEC11A	TMA7	ENSP00000268220	ENSP00000397843	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	translational machinery associated 7 homolog (S. cerevisiae)	0.418
TMA7	COMMD4	ENSP00000397843	ENSP00000267935	translational machinery associated 7 homolog (S. cerevisiae)	COMM domain containing 4; Down-regulates activation of NF-kappa-B	0.584
TMA7	SEC11A	ENSP00000397843	ENSP00000268220	translational machinery associated 7 homolog (S. cerevisiae)	SEC11 homolog A (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity)	0.418
TMA7	UBE2D4	ENSP00000397843	ENSP00000222402	translational machinery associated 7 homolog (S. cerevisiae)	ubiquitin-conjugating enzyme E2D 4 (putative); Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer ’Lys-11’ and ’Lys-48’-linked polyubiquitination	0.504
UBE2D4	COMMD4	ENSP00000222402	ENSP00000267935	ubiquitin-conjugating enzyme E2D 4 (putative); Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer ’Lys-11’ and ’Lys-48’-linked polyubiquitination	COMM domain containing 4; Down-regulates activation of NF-kappa-B	0.501
UBE2D4	TMA7	ENSP00000222402	ENSP00000397843	ubiquitin-conjugating enzyme E2D 4 (putative); Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer ’Lys-11’ and ’Lys-48’-linked polyubiquitination	translational machinery associated 7 homolog (S. cerevisiae)	0.504

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