node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANP32E | CADPS2 | ENSP00000324074 | ENSP00000398481 | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | Ca++-dependent secretion activator 2 | 0.485 |
AUTS2 | CADPS2 | ENSP00000344087 | ENSP00000398481 | autism susceptibility candidate 2 | Ca++-dependent secretion activator 2 | 0.860 |
AUTS2 | DYRK1A | ENSP00000344087 | ENSP00000381932 | autism susceptibility candidate 2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | 0.745 |
AUTS2 | NRG3 | ENSP00000344087 | ENSP00000361214 | autism susceptibility candidate 2 | neuregulin 3; Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes | 0.758 |
BDNF | CADPS2 | ENSP00000414303 | ENSP00000398481 | brain-derived neurotrophic factor | Ca++-dependent secretion activator 2 | 0.686 |
BDNF | DRD2 | ENSP00000414303 | ENSP00000354859 | brain-derived neurotrophic factor | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | 0.625 |
CADPS2 | ANP32E | ENSP00000398481 | ENSP00000324074 | Ca++-dependent secretion activator 2 | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity (By similarity) | 0.485 |
CADPS2 | AUTS2 | ENSP00000398481 | ENSP00000344087 | Ca++-dependent secretion activator 2 | autism susceptibility candidate 2 | 0.860 |
CADPS2 | BDNF | ENSP00000398481 | ENSP00000414303 | Ca++-dependent secretion activator 2 | brain-derived neurotrophic factor | 0.686 |
CADPS2 | DCTN1 | ENSP00000398481 | ENSP00000354791 | Ca++-dependent secretion activator 2 | dynactin 1 | 0.483 |
CADPS2 | DMD | ENSP00000398481 | ENSP00000354923 | Ca++-dependent secretion activator 2 | dystrophin | 0.603 |
CADPS2 | DRD2 | ENSP00000398481 | ENSP00000354859 | Ca++-dependent secretion activator 2 | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | 0.590 |
CADPS2 | DYRK1A | ENSP00000398481 | ENSP00000381932 | Ca++-dependent secretion activator 2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1 and SIRT1 | 0.757 |
CADPS2 | NRG3 | ENSP00000398481 | ENSP00000361214 | Ca++-dependent secretion activator 2 | neuregulin 3; Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes | 0.846 |
CADPS2 | RAB39B | ENSP00000398481 | ENSP00000358466 | Ca++-dependent secretion activator 2 | RAB39B, member RAS oncogene family; May be involved in vesicular trafficking. Plays a role in synapse formation (By similarity) | 0.461 |
CADPS2 | TSPAN12 | ENSP00000398481 | ENSP00000222747 | Ca++-dependent secretion activator 2 | tetraspanin 12; Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also p [...] | 0.498 |
DCTN1 | CADPS2 | ENSP00000354791 | ENSP00000398481 | dynactin 1 | Ca++-dependent secretion activator 2 | 0.483 |
DMD | CADPS2 | ENSP00000354923 | ENSP00000398481 | dystrophin | Ca++-dependent secretion activator 2 | 0.603 |
DRD2 | BDNF | ENSP00000354859 | ENSP00000414303 | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | brain-derived neurotrophic factor | 0.625 |
DRD2 | CADPS2 | ENSP00000354859 | ENSP00000398481 | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | Ca++-dependent secretion activator 2 | 0.590 |