node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CPT2 | L3MBTL1 | ENSP00000360541 | ENSP00000398516 | carnitine palmitoyltransferase 2 | l(3)mbt-like 1 (Drosophila) | 0.743 |
ELAVL2 | ELAVL3 | ENSP00000369460 | ENSP00000352162 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance | 0.622 |
ELAVL2 | L3MBTL1 | ENSP00000369460 | ENSP00000398516 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR | l(3)mbt-like 1 (Drosophila) | 0.758 |
ELAVL3 | ELAVL2 | ENSP00000352162 | ENSP00000369460 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR | 0.622 |
ELAVL3 | L3MBTL1 | ENSP00000352162 | ENSP00000398516 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance | l(3)mbt-like 1 (Drosophila) | 0.745 |
ETV7 | L3MBTL1 | ENSP00000341843 | ENSP00000398516 | ets variant 7 | l(3)mbt-like 1 (Drosophila) | 0.914 |
HIST1H1B | HIST1H4A | ENSP00000330074 | ENSP00000352980 | histone cluster 1, H1b; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | histone cluster 1, H4a | 0.730 |
HIST1H1B | L3MBTL1 | ENSP00000330074 | ENSP00000398516 | histone cluster 1, H1b; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | l(3)mbt-like 1 (Drosophila) | 0.750 |
HIST1H1E | HIST1H4A | ENSP00000307705 | ENSP00000352980 | histone cluster 1, H1e; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | histone cluster 1, H4a | 0.847 |
HIST1H1E | L3MBTL1 | ENSP00000307705 | ENSP00000398516 | histone cluster 1, H1e; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | l(3)mbt-like 1 (Drosophila) | 0.883 |
HIST1H4A | HIST1H1B | ENSP00000352980 | ENSP00000330074 | histone cluster 1, H4a | histone cluster 1, H1b; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | 0.730 |
HIST1H4A | HIST1H1E | ENSP00000352980 | ENSP00000307705 | histone cluster 1, H4a | histone cluster 1, H1e; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | 0.847 |
HIST1H4A | L3MBTL1 | ENSP00000352980 | ENSP00000398516 | histone cluster 1, H4a | l(3)mbt-like 1 (Drosophila) | 0.777 |
HIST1H4A | MSL3 | ENSP00000352980 | ENSP00000312244 | histone cluster 1, H4a | male-specific lethal 3 homolog (Drosophila); May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at ’Lys-16’ which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at ’Lys-20’ (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex | 0.628 |
HIST1H4A | SETD8 | ENSP00000352980 | ENSP00000332995 | histone cluster 1, H4a | SET domain containing (lysine methyltransferase) 8; Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates ’Lys-20’ of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome conden [...] | 0.994 |
L3MBTL1 | CPT2 | ENSP00000398516 | ENSP00000360541 | l(3)mbt-like 1 (Drosophila) | carnitine palmitoyltransferase 2 | 0.743 |
L3MBTL1 | ELAVL2 | ENSP00000398516 | ENSP00000369460 | l(3)mbt-like 1 (Drosophila) | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR | 0.758 |
L3MBTL1 | ELAVL3 | ENSP00000398516 | ENSP00000352162 | l(3)mbt-like 1 (Drosophila) | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance | 0.745 |
L3MBTL1 | ETV7 | ENSP00000398516 | ENSP00000341843 | l(3)mbt-like 1 (Drosophila) | ets variant 7 | 0.914 |
L3MBTL1 | HIST1H1B | ENSP00000398516 | ENSP00000330074 | l(3)mbt-like 1 (Drosophila) | histone cluster 1, H1b; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) | 0.750 |