TSTA3 protein (Homo sapiens) - STRING network view

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TSTA3

tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction (321 aa)

Predicted Functional Partners:

GMDS

0.997

FPGT

0.951

UBC

0.927

GMPPB

0.691

GNE

0.683

UGDH

0.660

DNAJC9

0.644

DSTN

0.644

CAD

0.602

GMPS

0.599

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAD	GMPS	ENSP00000264705	ENSP00000419851	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	0.992
CAD	TSTA3	ENSP00000264705	ENSP00000398803	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.602
CAD	UBC	ENSP00000264705	ENSP00000344818	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ubiquitin C	0.874
DNAJC9	TSTA3	ENSP00000362041	ENSP00000398803	DnaJ (Hsp40) homolog, subfamily C, member 9	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.644
DNAJC9	UBC	ENSP00000362041	ENSP00000344818	DnaJ (Hsp40) homolog, subfamily C, member 9	ubiquitin C	0.807
DSTN	TSTA3	ENSP00000246069	ENSP00000398803	destrin (actin depolymerizing factor); Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH- independent manner	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.644
DSTN	UBC	ENSP00000246069	ENSP00000344818	destrin (actin depolymerizing factor); Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH- independent manner	ubiquitin C	0.969
FPGT	TSTA3	ENSP00000359935	ENSP00000398803	fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.951
GMDS	GMPPB	ENSP00000370194	ENSP00000309092	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	GDP-mannose pyrophosphorylase B	0.940
GMDS	TSTA3	ENSP00000370194	ENSP00000398803	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.997
GMDS	UBC	ENSP00000370194	ENSP00000344818	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	ubiquitin C	0.620
GMDS	UGDH	ENSP00000370194	ENSP00000319501	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate	0.570
GMPPB	GMDS	ENSP00000309092	ENSP00000370194	GDP-mannose pyrophosphorylase B	GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	0.940
GMPPB	GNE	ENSP00000309092	ENSP00000379839	GDP-mannose pyrophosphorylase B	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	0.711
GMPPB	TSTA3	ENSP00000309092	ENSP00000398803	GDP-mannose pyrophosphorylase B	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.691
GMPPB	UBC	ENSP00000309092	ENSP00000344818	GDP-mannose pyrophosphorylase B	ubiquitin C	0.842
GMPS	CAD	ENSP00000419851	ENSP00000264705	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	0.992
GMPS	TSTA3	ENSP00000419851	ENSP00000398803	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	tissue specific transplantation antigen P35B; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	0.599
GMPS	UBC	ENSP00000419851	ENSP00000344818	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	ubiquitin C	0.983
GNE	GMPPB	ENSP00000379839	ENSP00000309092	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	GDP-mannose pyrophosphorylase B	0.711

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