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STRINGSTRING
MYL10 MYL10 CAMK2N1 CAMK2N1 CYBASC3 CYBASC3 ZNF45 ZNF45 ZNF235 ZNF235 POLR2G POLR2G ZNF224 ZNF224 TAX1BP3 TAX1BP3 ZNF225 ZNF225
"CYBASC3" - cytochrome b, ascorbate dependent 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CYBASC3cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) (259 aa)    
Predicted Functional Partners:
ZNF235
zinc finger protein 235; May be involved in transcriptional regulation (738 aa)
            score_image   0.655
POLR2G
polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] (172 aa)
            score_image   0.530
ZNF224
zinc finger protein 224; May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells (707 aa)
            score_image   0.504
ZNF45
zinc finger protein 45; May be involved in transcriptional regulation (682 aa)
            score_image   0.504
ZNF225
zinc finger protein 225; May be involved in transcriptional regulation (706 aa)
            score_image   0.504
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6 (124 aa)
            score_image   0.498
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1; Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity) (78 aa)
            score_image   0.455
MYL10
myosin, light chain 10, regulatory (226 aa)
            score_image   0.431
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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