node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAMK2N1 | CYBASC3 | ENSP00000364219 | ENSP00000398979 | calcium/calmodulin-dependent protein kinase II inhibitor 1; Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity) | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | 0.455 |
CAMK2N1 | ZNF235 | ENSP00000364219 | ENSP00000291182 | calcium/calmodulin-dependent protein kinase II inhibitor 1; Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity) | zinc finger protein 235; May be involved in transcriptional regulation | 0.488 |
CYBASC3 | CAMK2N1 | ENSP00000398979 | ENSP00000364219 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | calcium/calmodulin-dependent protein kinase II inhibitor 1; Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity) | 0.455 |
CYBASC3 | MYL10 | ENSP00000398979 | ENSP00000223167 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | myosin, light chain 10, regulatory | 0.431 |
CYBASC3 | POLR2G | ENSP00000398979 | ENSP00000301788 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | 0.530 |
CYBASC3 | TAX1BP3 | ENSP00000398979 | ENSP00000225525 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | Tax1 (human T-cell leukemia virus type I) binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6 | 0.498 |
CYBASC3 | ZNF224 | ENSP00000398979 | ENSP00000337368 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | zinc finger protein 224; May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells | 0.504 |
CYBASC3 | ZNF225 | ENSP00000398979 | ENSP00000262894 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | zinc finger protein 225; May be involved in transcriptional regulation | 0.504 |
CYBASC3 | ZNF235 | ENSP00000398979 | ENSP00000291182 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | zinc finger protein 235; May be involved in transcriptional regulation | 0.655 |
CYBASC3 | ZNF45 | ENSP00000398979 | ENSP00000269973 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | zinc finger protein 45; May be involved in transcriptional regulation | 0.504 |
MYL10 | CYBASC3 | ENSP00000223167 | ENSP00000398979 | myosin, light chain 10, regulatory | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | 0.431 |
POLR2G | CYBASC3 | ENSP00000301788 | ENSP00000398979 | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | 0.530 |
POLR2G | ZNF224 | ENSP00000301788 | ENSP00000337368 | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | zinc finger protein 224; May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells | 0.426 |
POLR2G | ZNF225 | ENSP00000301788 | ENSP00000262894 | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | zinc finger protein 225; May be involved in transcriptional regulation | 0.426 |
POLR2G | ZNF235 | ENSP00000301788 | ENSP00000291182 | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | zinc finger protein 235; May be involved in transcriptional regulation | 0.510 |
POLR2G | ZNF45 | ENSP00000301788 | ENSP00000269973 | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | zinc finger protein 45; May be involved in transcriptional regulation | 0.426 |
TAX1BP3 | CYBASC3 | ENSP00000225525 | ENSP00000398979 | Tax1 (human T-cell leukemia virus type I) binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6 | cytochrome b, ascorbate dependent 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm. Probably uses ascorbate as electron donor (By similarity) | 0.498 |
TAX1BP3 | ZNF224 | ENSP00000225525 | ENSP00000337368 | Tax1 (human T-cell leukemia virus type I) binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6 | zinc finger protein 224; May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells | 0.435 |
TAX1BP3 | ZNF225 | ENSP00000225525 | ENSP00000262894 | Tax1 (human T-cell leukemia virus type I) binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6 | zinc finger protein 225; May be involved in transcriptional regulation | 0.412 |
TAX1BP3 | ZNF235 | ENSP00000225525 | ENSP00000291182 | Tax1 (human T-cell leukemia virus type I) binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6 | zinc finger protein 235; May be involved in transcriptional regulation | 0.533 |