node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BOP1 | BRIX1 | ENSP00000304151 | ENSP00000338862 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | 0.989 |
BOP1 | ENSG00000248354 | ENSP00000304151 | ENSP00000415634 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | Uncharacterized protein | 0.943 |
BOP1 | GRWD1 | ENSP00000304151 | ENSP00000253237 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | glutamate-rich WD repeat containing 1 | 0.995 |
BOP1 | KIAA0020 | ENSP00000304151 | ENSP00000380982 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | KIAA0020 | 0.984 |
BOP1 | NOC2L | ENSP00000304151 | ENSP00000317992 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter | 0.984 |
BOP1 | PWP2 | ENSP00000304151 | ENSP00000291576 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | PWP2 periodic tryptophan protein homolog (yeast) | 0.943 |
BOP1 | RRP12 | ENSP00000304151 | ENSP00000360031 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.940 |
BOP1 | TEX13A | ENSP00000304151 | ENSP00000399753 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | testis expressed 13A | 0.741 |
BOP1 | TSR1 | ENSP00000304151 | ENSP00000301364 | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) | 0.966 |
BRIX1 | BOP1 | ENSP00000338862 | ENSP00000304151 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | block of proliferation 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome | 0.989 |
BRIX1 | ENSG00000204775 | ENSP00000338862 | ENSP00000366629 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | KM-PA-2 protein; Uncharacterized protein | 0.989 |
BRIX1 | ENSG00000248354 | ENSP00000338862 | ENSP00000415634 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | Uncharacterized protein | 0.896 |
BRIX1 | GRWD1 | ENSP00000338862 | ENSP00000253237 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | glutamate-rich WD repeat containing 1 | 0.984 |
BRIX1 | KIAA0020 | ENSP00000338862 | ENSP00000380982 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | KIAA0020 | 0.989 |
BRIX1 | NOC2L | ENSP00000338862 | ENSP00000317992 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | nucleolar complex associated 2 homolog (S. cerevisiae); Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter | 0.993 |
BRIX1 | PWP2 | ENSP00000338862 | ENSP00000291576 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | PWP2 periodic tryptophan protein homolog (yeast) | 0.897 |
BRIX1 | RRP12 | ENSP00000338862 | ENSP00000360031 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.961 |
BRIX1 | TEX13A | ENSP00000338862 | ENSP00000399753 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | testis expressed 13A | 0.745 |
BRIX1 | TSR1 | ENSP00000338862 | ENSP00000301364 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) | 0.957 |
ENSG00000204775 | BRIX1 | ENSP00000366629 | ENSP00000338862 | KM-PA-2 protein; Uncharacterized protein | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | 0.989 |