Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | NBEAL1 | neurobeachin-like 1 (2694 aa) | ||||||||||||
Predicted Functional Partners:
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 | GPR128 | G protein-coupled receptor 128; Orphan receptor (797 aa) |
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0.576 | ||||||||||
 | UHRF1BP1L | UHRF1 binding protein 1-like (1464 aa) |
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0.561 | ||||||||||
 | RHBDL1 | rhomboid, veinlet-like 1 (Drosophila); May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors (By similarity) (438 aa) |
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0.517 | ||||||||||
 | OR8D1 | olfactory receptor, family 8, subfamily D, member 1; Odorant receptor (Potential). May be involved in taste perception (308 aa) |
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0.499 | ||||||||||
 | ZYG11A | zyg-11 homolog A (C. elegans); Probably acts as target recruitment subunit in an E3 ubiquitin ligase complex ZYGA-CUL2-elongin BC (By similarity) (759 aa) |
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0.489 | ||||||||||
 | SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (3571 aa) |
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0.468 | ||||||||||
 | LRRC3 | leucine rich repeat containing 3 (257 aa) |
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0.430 | ||||||||||
 | ATG5 | autophagy related 5; Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity) (275 aa) |
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0.428 | ||||||||||
 | POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) (534 aa) |
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0.418 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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